Anaphylaxis-induced premature uterine contractions: a case report and literature review
Abstract Background Preterm labor is caused by multiple etiologies, including intra-amniotic infection and/or intra-amniotic inflammation, vascular disorders, cervical disease, decidual senescence, and breakdown of maternal–fetal tolerance. Accumulating evidence in vivo and in vitro has shown that a...
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | BMC Pregnancy and Childbirth |
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| Online Access: | https://doi.org/10.1186/s12884-024-06297-2 |
| _version_ | 1827315680288964608 |
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| author | Puntabut Warintaksa Waranyu Lertrat Roberto Romero Pornpun Vivithanaporn Paninee Mongkolsuk Threebhorn Kamlungkuea Rapeewan Settacomkul Pisut Pongchaikul Piya Chaemsaithong |
| author_facet | Puntabut Warintaksa Waranyu Lertrat Roberto Romero Pornpun Vivithanaporn Paninee Mongkolsuk Threebhorn Kamlungkuea Rapeewan Settacomkul Pisut Pongchaikul Piya Chaemsaithong |
| author_sort | Puntabut Warintaksa |
| collection | DOAJ |
| description | Abstract Background Preterm labor is caused by multiple etiologies, including intra-amniotic infection and/or intra-amniotic inflammation, vascular disorders, cervical disease, decidual senescence, and breakdown of maternal–fetal tolerance. Accumulating evidence in vivo and in vitro has shown that an allergic reaction, including anaphylaxis, can induce preterm uterine contractions. This report describes a case of a pregnant woman who developed anaphylaxis and regular uterine contractions after the ingestion of a strawberry-coated biscuit. We also review the mechanism of allergic reaction (hypersensitivity)-induced preterm labor. Case presentation A 31-year-old woman (gravida 1, para 0) at 30+2 weeks of gestation was admitted to the labor and delivery unit with regular uterine contractions and anaphylactic symptoms after she ingested a strawberry-coated biscuit as a snack. The uterine contractions resolved after the treatment of anaphylaxis by administering antihistamines and epinephrine. The patient subsequently delivered at 39+3 weeks of gestation. The amniotic fluid profile showed no infection or inflammation. A postpartum skin-prick test confirmed a positive type 1 hypersensitivity reaction to the strawberry-coated biscuit. Conclusions We report a case of anaphylaxis-induced uterine contractility in which uterine contractions subsided after the treatment of anaphylaxis. The absence of intra-amniotic infection and/or intra-amniotic inflammation and the cause of the anaphylaxis were confirmed. Our findings indicate that maternal allergic reactions may be one of the mechanisms of preterm labor. |
| first_indexed | 2024-04-24T23:01:36Z |
| format | Article |
| id | doaj.art-7688a4e698d2446088dfab22f0f3a2d4 |
| institution | Directory Open Access Journal |
| issn | 1471-2393 |
| language | English |
| last_indexed | 2024-04-24T23:01:36Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj.art-7688a4e698d2446088dfab22f0f3a2d42024-03-17T12:41:38ZengBMCBMC Pregnancy and Childbirth1471-23932024-03-012411910.1186/s12884-024-06297-2Anaphylaxis-induced premature uterine contractions: a case report and literature reviewPuntabut Warintaksa0Waranyu Lertrat1Roberto Romero2Pornpun Vivithanaporn3Paninee Mongkolsuk4Threebhorn Kamlungkuea5Rapeewan Settacomkul6Pisut Pongchaikul7Piya Chaemsaithong8Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityDepartment of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityPregnancy Research Branch, Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, U.S, Department of Health and Human Services (NICHD/NIH/DHHS)Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital Mahidol UniversityChakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital Mahidol UniversityDepartment of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityChakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital Mahidol UniversityChakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital Mahidol UniversityDepartment of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityAbstract Background Preterm labor is caused by multiple etiologies, including intra-amniotic infection and/or intra-amniotic inflammation, vascular disorders, cervical disease, decidual senescence, and breakdown of maternal–fetal tolerance. Accumulating evidence in vivo and in vitro has shown that an allergic reaction, including anaphylaxis, can induce preterm uterine contractions. This report describes a case of a pregnant woman who developed anaphylaxis and regular uterine contractions after the ingestion of a strawberry-coated biscuit. We also review the mechanism of allergic reaction (hypersensitivity)-induced preterm labor. Case presentation A 31-year-old woman (gravida 1, para 0) at 30+2 weeks of gestation was admitted to the labor and delivery unit with regular uterine contractions and anaphylactic symptoms after she ingested a strawberry-coated biscuit as a snack. The uterine contractions resolved after the treatment of anaphylaxis by administering antihistamines and epinephrine. The patient subsequently delivered at 39+3 weeks of gestation. The amniotic fluid profile showed no infection or inflammation. A postpartum skin-prick test confirmed a positive type 1 hypersensitivity reaction to the strawberry-coated biscuit. Conclusions We report a case of anaphylaxis-induced uterine contractility in which uterine contractions subsided after the treatment of anaphylaxis. The absence of intra-amniotic infection and/or intra-amniotic inflammation and the cause of the anaphylaxis were confirmed. Our findings indicate that maternal allergic reactions may be one of the mechanisms of preterm labor.https://doi.org/10.1186/s12884-024-06297-2AllergyAmniotic fluidAnaphylaxisContractilityContractionHypersensitivity |
| spellingShingle | Puntabut Warintaksa Waranyu Lertrat Roberto Romero Pornpun Vivithanaporn Paninee Mongkolsuk Threebhorn Kamlungkuea Rapeewan Settacomkul Pisut Pongchaikul Piya Chaemsaithong Anaphylaxis-induced premature uterine contractions: a case report and literature review BMC Pregnancy and Childbirth Allergy Amniotic fluid Anaphylaxis Contractility Contraction Hypersensitivity |
| title | Anaphylaxis-induced premature uterine contractions: a case report and literature review |
| title_full | Anaphylaxis-induced premature uterine contractions: a case report and literature review |
| title_fullStr | Anaphylaxis-induced premature uterine contractions: a case report and literature review |
| title_full_unstemmed | Anaphylaxis-induced premature uterine contractions: a case report and literature review |
| title_short | Anaphylaxis-induced premature uterine contractions: a case report and literature review |
| title_sort | anaphylaxis induced premature uterine contractions a case report and literature review |
| topic | Allergy Amniotic fluid Anaphylaxis Contractility Contraction Hypersensitivity |
| url | https://doi.org/10.1186/s12884-024-06297-2 |
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