Evaluation of sleep quality and pruritus severity in psoriatic patients and their impact on quality of life: a cross section correlational study
Abstract Psoriasis is a chronic inflammatory condition associated with genetic and immunological susceptibility. The objective of the study was to evaluate pruritus and sleep quality in correlation (r) to psoriasis severity and to detect their impact on quality of life. Two hundred (200) patients wi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-10-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-44757-5 |
| _version_ | 1797452724302774272 |
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| author | Mohamed S. Zaky Emad Eldin A. Elgamal Ayman A. Abd Al Maksoud Dina H. Mohamed Mohamed L. Elsaie |
| author_facet | Mohamed S. Zaky Emad Eldin A. Elgamal Ayman A. Abd Al Maksoud Dina H. Mohamed Mohamed L. Elsaie |
| author_sort | Mohamed S. Zaky |
| collection | DOAJ |
| description | Abstract Psoriasis is a chronic inflammatory condition associated with genetic and immunological susceptibility. The objective of the study was to evaluate pruritus and sleep quality in correlation (r) to psoriasis severity and to detect their impact on quality of life. Two hundred (200) patients with psoriasis were included. Psoriasis severity was determined using the psoriasis area severity index (PASI), the quality of life (QoL) was assessed by the psoriasis disability index (PDI) questionnaire, and the sleep quality was evaluated by the Pittsburgh sleep quality index (PSQI). Finally, the severity of itching was evaluated using a 12-item pruritus severity scale (PSS). Poor sleep quality was found in 16.0% of patients in this study. Poor sleep was detected among 50.0% of cases with severe psoriasis. PASI scores correlated significantly with sleep quality, duration and sleep disturbances (p < 0.001). The global PSQI and PASI were also significantly correlated (p = 0.004). In conclusion patients complaining of psoriasis exacerbated by pruritus and sleep problems demonstrated lower quality of life in all domains. Sleep disturbances and depressive symptoms impairing quality of life should be taken into consideration when screening patients suffering from psoriasis. |
| first_indexed | 2024-03-09T15:12:47Z |
| format | Article |
| id | doaj.art-768ed31037344c9696ac73fcfefb8f63 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-09T15:12:47Z |
| publishDate | 2023-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-768ed31037344c9696ac73fcfefb8f632023-11-26T13:17:11ZengNature PortfolioScientific Reports2045-23222023-10-0113111310.1038/s41598-023-44757-5Evaluation of sleep quality and pruritus severity in psoriatic patients and their impact on quality of life: a cross section correlational studyMohamed S. Zaky0Emad Eldin A. Elgamal1Ayman A. Abd Al Maksoud2Dina H. Mohamed3Mohamed L. Elsaie4Department of Dermatology, Venereology and Andrology, Damietta Faculty of Medicine, Al-Azhar UniversityDepartment of Dermatology, Venereology and Andrology, Damietta Faculty of Medicine, Al-Azhar UniversityDepartment of Psychiatry, Damietta Faculty of Medicine, Al-Azhar UniversityDepartment of Dermatology, Venereology and Andrology, Damietta Faculty of Medicine, Al-Azhar UniversityDepartment of Dermatology, Venereology and Andrology, Medical Research and Clinical Studies Institute, National Research CentreAbstract Psoriasis is a chronic inflammatory condition associated with genetic and immunological susceptibility. The objective of the study was to evaluate pruritus and sleep quality in correlation (r) to psoriasis severity and to detect their impact on quality of life. Two hundred (200) patients with psoriasis were included. Psoriasis severity was determined using the psoriasis area severity index (PASI), the quality of life (QoL) was assessed by the psoriasis disability index (PDI) questionnaire, and the sleep quality was evaluated by the Pittsburgh sleep quality index (PSQI). Finally, the severity of itching was evaluated using a 12-item pruritus severity scale (PSS). Poor sleep quality was found in 16.0% of patients in this study. Poor sleep was detected among 50.0% of cases with severe psoriasis. PASI scores correlated significantly with sleep quality, duration and sleep disturbances (p < 0.001). The global PSQI and PASI were also significantly correlated (p = 0.004). In conclusion patients complaining of psoriasis exacerbated by pruritus and sleep problems demonstrated lower quality of life in all domains. Sleep disturbances and depressive symptoms impairing quality of life should be taken into consideration when screening patients suffering from psoriasis.https://doi.org/10.1038/s41598-023-44757-5 |
| spellingShingle | Mohamed S. Zaky Emad Eldin A. Elgamal Ayman A. Abd Al Maksoud Dina H. Mohamed Mohamed L. Elsaie Evaluation of sleep quality and pruritus severity in psoriatic patients and their impact on quality of life: a cross section correlational study Scientific Reports |
| title | Evaluation of sleep quality and pruritus severity in psoriatic patients and their impact on quality of life: a cross section correlational study |
| title_full | Evaluation of sleep quality and pruritus severity in psoriatic patients and their impact on quality of life: a cross section correlational study |
| title_fullStr | Evaluation of sleep quality and pruritus severity in psoriatic patients and their impact on quality of life: a cross section correlational study |
| title_full_unstemmed | Evaluation of sleep quality and pruritus severity in psoriatic patients and their impact on quality of life: a cross section correlational study |
| title_short | Evaluation of sleep quality and pruritus severity in psoriatic patients and their impact on quality of life: a cross section correlational study |
| title_sort | evaluation of sleep quality and pruritus severity in psoriatic patients and their impact on quality of life a cross section correlational study |
| url | https://doi.org/10.1038/s41598-023-44757-5 |
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