A Synopsis Clonal Hematopoiesis of Indeterminate Potential in Hematology
Clonal hematopoiesis of indeterminate potential can be defined as genetic mutations that correlate in hematologic neoplasia such as myelodysplastic syndrome. Patients with cytopenia increasingly undergo molecular genetic tests of peripheral blood or bone marrow for diagnostic purposes. Recently, a n...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/14/15/3663 |
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| author | Maroun Bou Zerdan Lewis Nasr Ludovic Saba Paul Meouchy Nadine Safi Sabine Allam Jenish Bhandari Chakra P. Chaulagain |
| author_facet | Maroun Bou Zerdan Lewis Nasr Ludovic Saba Paul Meouchy Nadine Safi Sabine Allam Jenish Bhandari Chakra P. Chaulagain |
| author_sort | Maroun Bou Zerdan |
| collection | DOAJ |
| description | Clonal hematopoiesis of indeterminate potential can be defined as genetic mutations that correlate in hematologic neoplasia such as myelodysplastic syndrome. Patients with cytopenia increasingly undergo molecular genetic tests of peripheral blood or bone marrow for diagnostic purposes. Recently, a new entity has been demarcated to lessen the risk of incorrect diagnoses of hematologic malignancies. This new entity is a potential precursor of myeloid diseases, analogous to monoclonal gammopathy of undetermined significance as a potential precursor of multiple myeloma. |
| first_indexed | 2024-03-09T10:09:31Z |
| format | Article |
| id | doaj.art-769030f72ecc40fcace70a1157756c6b |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-09T10:09:31Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-769030f72ecc40fcace70a1157756c6b2023-12-01T22:51:55ZengMDPI AGCancers2072-66942022-07-011415366310.3390/cancers14153663A Synopsis Clonal Hematopoiesis of Indeterminate Potential in HematologyMaroun Bou Zerdan0Lewis Nasr1Ludovic Saba2Paul Meouchy3Nadine Safi4Sabine Allam5Jenish Bhandari6Chakra P. Chaulagain7Department of Internal Medicine, SUNY Upstate Medical University, New York, NY 10009, USAFaculty of Medicine, Saint-Joseph University, Beirut P.O. Box 100, LebanonFaculty of Medicine, Saint-Joseph University, Beirut P.O. Box 100, LebanonDepartment of Internal Medicine, Division of Hematology and Oncology, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, Beirut P.O. Box 100, LebanonDepartment of Internal Medicine, Division of Hematology and Oncology, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, Beirut P.O. Box 100, LebanonDepartment of Medicine and Medical Sciences, University of Balamand, Balamand P.O. Box 100, LebanonDepartment of Internal Medicine, SUNY Upstate Medical University, New York, NY 10009, USADepartment of Hematology-Oncology, Myeloma and Amyloidosis Program, Maroone Cancer Center, Cleveland Clinic Florida, Weston, FL 33326, USAClonal hematopoiesis of indeterminate potential can be defined as genetic mutations that correlate in hematologic neoplasia such as myelodysplastic syndrome. Patients with cytopenia increasingly undergo molecular genetic tests of peripheral blood or bone marrow for diagnostic purposes. Recently, a new entity has been demarcated to lessen the risk of incorrect diagnoses of hematologic malignancies. This new entity is a potential precursor of myeloid diseases, analogous to monoclonal gammopathy of undetermined significance as a potential precursor of multiple myeloma.https://www.mdpi.com/2072-6694/14/15/3663clonal hematopoeisischimeric antigen receptor T-cell therapymutationshematologymyeloma |
| spellingShingle | Maroun Bou Zerdan Lewis Nasr Ludovic Saba Paul Meouchy Nadine Safi Sabine Allam Jenish Bhandari Chakra P. Chaulagain A Synopsis Clonal Hematopoiesis of Indeterminate Potential in Hematology Cancers clonal hematopoeisis chimeric antigen receptor T-cell therapy mutations hematology myeloma |
| title | A Synopsis Clonal Hematopoiesis of Indeterminate Potential in Hematology |
| title_full | A Synopsis Clonal Hematopoiesis of Indeterminate Potential in Hematology |
| title_fullStr | A Synopsis Clonal Hematopoiesis of Indeterminate Potential in Hematology |
| title_full_unstemmed | A Synopsis Clonal Hematopoiesis of Indeterminate Potential in Hematology |
| title_short | A Synopsis Clonal Hematopoiesis of Indeterminate Potential in Hematology |
| title_sort | synopsis clonal hematopoiesis of indeterminate potential in hematology |
| topic | clonal hematopoeisis chimeric antigen receptor T-cell therapy mutations hematology myeloma |
| url | https://www.mdpi.com/2072-6694/14/15/3663 |
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