Evaluation of Predicted siRNA as an Antiviral against MERS-CoV Targeting the Membrane Gene in the Vero Cell Line
The Middle East respiratory syndrome coronavirus (MERS-CoV) was first isolated from a patient with acute pneumonia and renal failure in Saudi Arabia in 2012. By July 2023, MERS-CoV had resulted in 2605 human cases worldwide, causing a fatality rate of 36%, with 90.2% of cases being located in the Ar...
Main Authors: | Amany Y. El-Sayed, Mahmoud Shehata, Sara H. Mahmoud, Mahmoud ElHefnawi, Dina M. Seoudi, Mohamed A. Ali |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-10-01
|
Series: | Microbiology Research |
Subjects: | |
Online Access: | https://www.mdpi.com/2036-7481/14/4/116 |
Similar Items
-
Delivery of siRNAs against MERS-CoV in Vero and HEK-293 cells: A comparative evaluation of transfection reagents
by: Sayed Sartaj Sohrab, et al.
Published: (2023-04-01) -
Designing and evaluation of MERS-CoV siRNAs in HEK-293 cell line
by: Sayed Sartaj Sohrab, et al.
Published: (2021-02-01) -
Computational Design and Experimental Evaluation of MERS-CoV siRNAs in Selected Cell Lines
by: Sayed S. Sohrab, et al.
Published: (2023-01-01) -
In Vitro Inhibitory Analysis of Rationally Designed siRNAs against MERS-CoV Replication in Huh7 Cells
by: Sherif Aly El-Kafrawy, et al.
Published: (2021-04-01) -
Current Aspects of siRNA Bioconjugate for In Vitro and In Vivo Delivery
by: Wanyi Tai
Published: (2019-06-01)