Alpha-mangostin counteracts hyperuricemia and renal dysfunction by inhibiting URAT1 renal transporter in insulin resistance rat model

Alpha-mangostin counteracts hyperuricemia and renal dysfunction by inhibiting URAT1 renal transporter in insulin resistance rat model

Abstract Background Alpha-mangostin (AM) has been shown to have hypoglycemic activity. This study aimed to analyze the effects of AM at a dose of 100 mg/kg and 200 mg/kg to alleviate hyperuricemia and renal dysfunction on high-fat/high-glucose diet and low dose streptozotocin (HF/HG/STZ) injection-i...

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Bibliographic Details
Main Authors: Vivian Soetikno, Andriyani Murwantara, Ahmad Aulia Jusuf, Melva Louisa
Format: Article
Language:English
Published: SpringerOpen 2022-07-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
Insulin sensitivity
Urate transporters
Hypouricosuria
Kidney
Proximal tubule
Online Access:https://doi.org/10.1186/s43088-022-00275-3

Internet

https://doi.org/10.1186/s43088-022-00275-3

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