Aflatoxin M1 Risk Assessment in Formula Product for Infants and Children Aged 036 month
Aflatoxin M1 (AFM1) is a carcinogenic compound found in milk-based products including infant and young children formula. The aim of this study was to determine the risk characterization of infants and young children to AFM1 through the consumption of formula products. For this purpose, the Estimated...
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| Format: | Article |
| Language: | English |
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Bogor Agricultural University
2020-01-01
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| Series: | Jurnal Ilmu Pertanian Indonesia |
| Subjects: | |
| Online Access: | https://journal.ipb.ac.id/index.php/JIPI/article/view/25485 |
| _version_ | 1818282598830440448 |
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| author | Yeni Restiani Lilis Nuraida Hanifah Nuryani Lioe |
| author_facet | Yeni Restiani Lilis Nuraida Hanifah Nuryani Lioe |
| author_sort | Yeni Restiani |
| collection | DOAJ |
| description | Aflatoxin M1 (AFM1) is a carcinogenic compound found in milk-based products including infant and young children formula. The aim of this study was to determine the risk characterization of infants and young children to AFM1 through the consumption of formula products. For this purpose, the Estimated Daily Intake (EDI) for infants and young children was calculated by multiplying AFM1 concentration in 44 infant formulas, 53 advanced infant formulas, and 16 growing up formulas with consumption data. The concentration of AFM1 in these formula products were retrieved from food registration in Indonesian FDA from January 2015June 2018. The average concentration of AFM1 in infant formula, advanced infant formulas, and growing up formula (lower bound-upper bound) were 0.02260.0335; 0.04180.0510; and 0.00380.0123 ng/g, respectively. The average EDI of AFM1 for infants and young children aged 06 months, 612 months, and 13 years based on individual consumption were 0.2600.386, 0.2820.343, 0.0290.092 ng/kg body weight (BW)/day. The average EDI of AFM1 for infants and young children aged 06 months, 612 months, and 13 years based on the recommended consumption by food producer (lower bound-upper bound) were 0.4030.598; 0.6630.809; 0.0310.098 ng/kgBW/day. The average hazard index (HI) values for infants aged 06 months and 612 months (lower bound-upper bound) were greater than 1 (one), i.e., 1.942.88 and 3.203.90, which indicates there is a health risk. However hazard index value for young children aged 13 years (lower bound-upper bound) were less than 1 (one), i.e., 0.150.47, which indicates a lower health risk. |
| first_indexed | 2024-12-13T00:23:34Z |
| format | Article |
| id | doaj.art-769ce35602c14770a76b6d4b8f0041e3 |
| institution | Directory Open Access Journal |
| issn | 0853-4217 2443-3462 |
| language | English |
| last_indexed | 2024-12-13T00:23:34Z |
| publishDate | 2020-01-01 |
| publisher | Bogor Agricultural University |
| record_format | Article |
| series | Jurnal Ilmu Pertanian Indonesia |
| spelling | doaj.art-769ce35602c14770a76b6d4b8f0041e32022-12-22T00:05:29ZengBogor Agricultural UniversityJurnal Ilmu Pertanian Indonesia0853-42172443-34622020-01-0125116016610.18343/jipi.25.1.160Aflatoxin M1 Risk Assessment in Formula Product for Infants and Children Aged 036 monthYeni Restiani0Lilis Nuraida1Hanifah Nuryani Lioe2Departemen Ilmu dan Teknologi Pangan, Fakultas Teknologi Pertanian, Institut Pertanian Bogor, Kampus IPB Darmaga, Bogor 16680Departemen Ilmu dan Teknologi Pangan, Fakultas Teknologi Pertanian, Institut Pertanian Bogor, Kampus IPB Darmaga, Bogor 16680Departemen Ilmu dan Teknologi Pangan, Fakultas Teknologi Pertanian, Institut Pertanian Bogor, Kampus IPB Darmaga, Bogor 16680Aflatoxin M1 (AFM1) is a carcinogenic compound found in milk-based products including infant and young children formula. The aim of this study was to determine the risk characterization of infants and young children to AFM1 through the consumption of formula products. For this purpose, the Estimated Daily Intake (EDI) for infants and young children was calculated by multiplying AFM1 concentration in 44 infant formulas, 53 advanced infant formulas, and 16 growing up formulas with consumption data. The concentration of AFM1 in these formula products were retrieved from food registration in Indonesian FDA from January 2015June 2018. The average concentration of AFM1 in infant formula, advanced infant formulas, and growing up formula (lower bound-upper bound) were 0.02260.0335; 0.04180.0510; and 0.00380.0123 ng/g, respectively. The average EDI of AFM1 for infants and young children aged 06 months, 612 months, and 13 years based on individual consumption were 0.2600.386, 0.2820.343, 0.0290.092 ng/kg body weight (BW)/day. The average EDI of AFM1 for infants and young children aged 06 months, 612 months, and 13 years based on the recommended consumption by food producer (lower bound-upper bound) were 0.4030.598; 0.6630.809; 0.0310.098 ng/kgBW/day. The average hazard index (HI) values for infants aged 06 months and 612 months (lower bound-upper bound) were greater than 1 (one), i.e., 1.942.88 and 3.203.90, which indicates there is a health risk. However hazard index value for young children aged 13 years (lower bound-upper bound) were less than 1 (one), i.e., 0.150.47, which indicates a lower health risk.https://journal.ipb.ac.id/index.php/JIPI/article/view/25485advanced infant formulaaflatoxin m1growing up formulahazard indexinfant formula |
| spellingShingle | Yeni Restiani Lilis Nuraida Hanifah Nuryani Lioe Aflatoxin M1 Risk Assessment in Formula Product for Infants and Children Aged 036 month Jurnal Ilmu Pertanian Indonesia advanced infant formula aflatoxin m1 growing up formula hazard index infant formula |
| title | Aflatoxin M1 Risk Assessment in Formula Product for Infants and Children Aged 036 month |
| title_full | Aflatoxin M1 Risk Assessment in Formula Product for Infants and Children Aged 036 month |
| title_fullStr | Aflatoxin M1 Risk Assessment in Formula Product for Infants and Children Aged 036 month |
| title_full_unstemmed | Aflatoxin M1 Risk Assessment in Formula Product for Infants and Children Aged 036 month |
| title_short | Aflatoxin M1 Risk Assessment in Formula Product for Infants and Children Aged 036 month |
| title_sort | aflatoxin m1 risk assessment in formula product for infants and children aged 036 month |
| topic | advanced infant formula aflatoxin m1 growing up formula hazard index infant formula |
| url | https://journal.ipb.ac.id/index.php/JIPI/article/view/25485 |
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