Lack of involvement of known DNA methyltransferases in familial hydatidiform mole implies the involvement of other factors in establishment of imprinting in the human female germline
<p>Abstract</p> <p>Background</p> <p>Differential methylation of the two alleles is a hallmark of imprinted genes. Correspondingly, loss of DNA methyltransferase function results in aberrant imprinting and abnormal post-fertilization development. In the mouse, mutations...
Main Authors: | Picton H M, Huntriss J, Hodge D, Judson H, De Vos M, Hayward B E, Sheridan E, Bonthron DT |
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Format: | Article |
Language: | English |
Published: |
BMC
2003-01-01
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Series: | BMC Genetics |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2156/4/2 |
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