Determination of Prevalence and Clinical Significance of Detection of Micro-organisms in Pap Smear with Seasonal Variation
Introduction: The most common problem in reproductive age group women is vaginitis. In the vaginal flora an extensive and diverse spectrum of pathogenic agents may be observed. The important infectious agents in vaginal flora are Bacterial Vaginosis (BV), Candida (Can) and Trichomonas vaginalis...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Pvt. Ltd.
2017-07-01
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| Series: | National Journal of Laboratory Medicine |
| Subjects: | |
| Online Access: | http://www.njlm.net/articles/PDF/2239/26474_CE[VSU]_F(GH)_PF(VSUAK)_PFA(AK)_PF2(VSU_GG).pdf |
| Summary: | Introduction: The most common problem in reproductive
age group women is vaginitis. In the vaginal flora an extensive
and diverse spectrum of pathogenic agents may be observed.
The important infectious agents in vaginal flora are Bacterial
Vaginosis (BV), Candida (Can) and Trichomonas vaginalis (TV).
The pap smear is a screening test to diagnose cervical cancer
and has also been used as a diagnostic test in cervical infection
caused by different pathogenic organisms.
Aim: To determine the prevalence and clinical significance of
micro-organisms in pap smears.
Materials and Methods: A two year retrospective Pap smear
study was done from January 2014 to December 2015, in a
tertiary care unit, Saveetha Medical College and Hospital,
Thandalam, Chennai, India. This study was undertaken to
determine the prevalence, clinical significance and seasonal
variation in cervicovaginal infections. The Chi-square test was
used for statistical analysis. A p-value of <0.05 was considered
significant for statistical evaluation.
Results: The total number of pap smears examined was
6424, out of which the total pap positive smears for infectious
organisms were 896(13.94%). The prevalence of organisms
among total infectious organisms is 51.4% (BV), 30% (Can),
12.4% (TV) and mixed infections 3.5% and 2.7% (BV+TV and
BV+Can). Comparison of seasonal variation in prevalence of
vaginal infectious agents was also analyzed.
Conclusion: It is concluded that cervical cytology is important
for diagnosis of cervical infections. The most important cause
of cervico-vaginitis are bacterial vaginosis, next important
cause is candidiasis. It is important to mobilize all reproductive
age women to undergo pap smear examination and to prevent
complications caused by infectious agents. |
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| ISSN: | 2277-8551 2455-6882 |