DNA Damage Response Differentially Affects BoHV-1 Gene Transcription in Cell Type-Dependent Manners

DNA Damage Response Differentially Affects BoHV-1 Gene Transcription in Cell Type-Dependent Manners

Bovine herpesvirus 1 (BoHV-1), an important pathogen of cattle, is also a promising oncolytic virus. Recent studies have demonstrated that the virus infection induces DNA damage and DNA damage response (DDR), potentially accounting for virus infection-induced cell death and oncolytic effects. Howeve...

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Bibliographic Details
Main Authors: Linke Tang, Weifeng Yuan, Shitao Li, Xiuyan Ding, Liqian Zhu
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
bovine herpesvirus 1
DNA damage
DNA damage response
γH2AX
ultraviolet
Online Access:https://www.mdpi.com/2227-9059/10/9/2282

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