Adamantinomatous craniopharyngioma cyst fluid can trigger inflammatory activation of microglia to damage the hypothalamic neurons by inducing the production of β-amyloid

Adamantinomatous craniopharyngioma cyst fluid can trigger inflammatory activation of microglia to damage the hypothalamic neurons by inducing the production of β-amyloid

Abstract Introduction The mechanism by which adamantinomatous craniopharyngioma (ACP) damages the hypothalamus is still unclear. Cyst fluid rich in lipids and inflammatory factors is a characteristic pathological manifestation of ACP and may play a very important role in hypothalamic injury caused b...

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Bibliographic Details
Main Authors: Yilamujiang Ainiwan, Yiguang Chen, Chaofu Mao, Junxiang Peng, Siyuan Chen, Songtao Wei, Songtao Qi, Jun Pan
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Journal of Neuroinflammation
Subjects:
Adamantinomatous Craniopharyngioma
Cyst Fluid
Hypothalamus
Single-Cell RNA Sequencing
Microglia
Inflammation
Online Access:https://doi.org/10.1186/s12974-022-02470-6

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