KBE009: A Bestatin-Like Inhibitor of the <i>Trypanosoma cruzi</i> Acidic M17 Aminopeptidase with In Vitro Anti-Trypanosomal Activity

KBE009: A Bestatin-Like Inhibitor of the <i>Trypanosoma cruzi</i> Acidic M17 Aminopeptidase with In Vitro Anti-Trypanosomal Activity

Chagas disease, caused by the kinetoplastid parasite <i>Trypanosoma cruzi</i>, is a human tropical illness mainly present in Latin America. The therapies available against this disease are far from ideal. Proteases from pathogenic protozoan have been considered as good drug target candid...

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Bibliographic Details
Main Authors: Jorge González-Bacerio, Irina Arocha, Mirtha Elisa Aguado, Yanira Méndez, Sabrina Marsiccobetre, Maikel Izquierdo, Daniel G. Rivera, Katherine Figarella, Néstor L. Uzcátegui
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Life
Subjects:
bestatin-like peptidomimetics
chemotherapy
leucyl-aminopeptidase
protease inhibitors
<i>Trypanosoma cruzi</i>
Online Access:https://www.mdpi.com/2075-1729/11/10/1037

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https://www.mdpi.com/2075-1729/11/10/1037

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