4DCT Differentiation of Parathyroid Adenoma: A Case Report

We report the case of a 72-year-old patient presenting with recurrent primary hyperparathyroidism after total thyroidectomy and parathyroidectomy with presternal autotransplantation. Methionine-PET-CT proved false-positive and Tc-99m-tetrofosmine imaging false-negative. Using a novel multiphase-4DCT...

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Main Authors: Tana Bupe Mwewa, Steven Raeymaeckers
Format: Article
Language:English
Published: Ubiquity Press 2023-08-01
Series:Journal of the Belgian Society of Radiology
Subjects:
Online Access:https://account.jbsr.be/index.php/up-j-jbsr/article/view/3238
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author Tana Bupe Mwewa
Steven Raeymaeckers
author_facet Tana Bupe Mwewa
Steven Raeymaeckers
author_sort Tana Bupe Mwewa
collection DOAJ
description We report the case of a 72-year-old patient presenting with recurrent primary hyperparathyroidism after total thyroidectomy and parathyroidectomy with presternal autotransplantation. Methionine-PET-CT proved false-positive and Tc-99m-tetrofosmine imaging false-negative. Using a novel multiphase-4DCT technique we identified an anterior mediastinal nodule demonstrating contrast wash-in and wash-out, suggesting parathyroid adenoma. Traditional 4DCT-protocols obtain fewer phases; therefore, this enhancement pattern might have gone unnoticed. After surgical resection the bloodwork normalized, histopathology confirmed a parathyroid adenoma. Teaching Point: Multiphase 4DCT is a potentially helpful technique for the detection of parathyroid adenomas after total thyroidectomy and parathyroidectomy.
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spelling doaj.art-76b4f93232ad42729669dbd49e007c422023-09-27T08:09:08ZengUbiquity PressJournal of the Belgian Society of Radiology2514-82812023-08-011071616110.5334/jbsr.323832324DCT Differentiation of Parathyroid Adenoma: A Case ReportTana Bupe Mwewa0https://orcid.org/0000-0003-3299-513XSteven Raeymaeckers1https://orcid.org/0000-0003-0822-1919UZ BrusselUZ BrusselWe report the case of a 72-year-old patient presenting with recurrent primary hyperparathyroidism after total thyroidectomy and parathyroidectomy with presternal autotransplantation. Methionine-PET-CT proved false-positive and Tc-99m-tetrofosmine imaging false-negative. Using a novel multiphase-4DCT technique we identified an anterior mediastinal nodule demonstrating contrast wash-in and wash-out, suggesting parathyroid adenoma. Traditional 4DCT-protocols obtain fewer phases; therefore, this enhancement pattern might have gone unnoticed. After surgical resection the bloodwork normalized, histopathology confirmed a parathyroid adenoma. Teaching Point: Multiphase 4DCT is a potentially helpful technique for the detection of parathyroid adenomas after total thyroidectomy and parathyroidectomy.https://account.jbsr.be/index.php/up-j-jbsr/article/view/3238cthead and neckhyperparathyroidismparathyroid adenoma
spellingShingle Tana Bupe Mwewa
Steven Raeymaeckers
4DCT Differentiation of Parathyroid Adenoma: A Case Report
Journal of the Belgian Society of Radiology
ct
head and neck
hyperparathyroidism
parathyroid adenoma
title 4DCT Differentiation of Parathyroid Adenoma: A Case Report
title_full 4DCT Differentiation of Parathyroid Adenoma: A Case Report
title_fullStr 4DCT Differentiation of Parathyroid Adenoma: A Case Report
title_full_unstemmed 4DCT Differentiation of Parathyroid Adenoma: A Case Report
title_short 4DCT Differentiation of Parathyroid Adenoma: A Case Report
title_sort 4dct differentiation of parathyroid adenoma a case report
topic ct
head and neck
hyperparathyroidism
parathyroid adenoma
url https://account.jbsr.be/index.php/up-j-jbsr/article/view/3238
work_keys_str_mv AT tanabupemwewa 4dctdifferentiationofparathyroidadenomaacasereport
AT stevenraeymaeckers 4dctdifferentiationofparathyroidadenomaacasereport