Serous adenocarcinoma of endometrium coexistence with atypical polypoid adenomyoma in a postmenopausal woman: A rare case

This work describes a rare case of serous carcinoma coexistence with atypical polypoid adenomyoma (APA). A 55-year-old postmenopausal woman presented with intermittent vaginal bleeding for 1 year. Her Pap test exhibited atypical glandular cell and endometrial biopsy showed serous carcinoma. She unde...

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Main Authors: Chiu-Shih Cheng, Yu-Chi Wei, Tang-Yuan Chu, Dah-Ching Ding
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Journal of Medical Sciences
Subjects:
Online Access:http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2016;volume=36;issue=4;spage=162;epage=164;aulast=Cheng
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author Chiu-Shih Cheng
Yu-Chi Wei
Tang-Yuan Chu
Dah-Ching Ding
author_facet Chiu-Shih Cheng
Yu-Chi Wei
Tang-Yuan Chu
Dah-Ching Ding
author_sort Chiu-Shih Cheng
collection DOAJ
description This work describes a rare case of serous carcinoma coexistence with atypical polypoid adenomyoma (APA). A 55-year-old postmenopausal woman presented with intermittent vaginal bleeding for 1 year. Her Pap test exhibited atypical glandular cell and endometrial biopsy showed serous carcinoma. She underwent a staging surgery, and the histopathology revealed serous carcinoma with p53 mutation and coexistence with APA staged as FIGO Stage Ia, Grade 1. The patient recovered well postoperatively. APA lesion is generally benign, but it may progress in rare cases to adenocarcinoma, usually endometrioid type. This is the first case report regarding serous carcinoma coexistence with APA. Therefore, the patient with APA should always be closely followed up. Nevertheless, further study is stipulated to better understand the clinicopathological features of serous adenocarcinoma coexisting with APA.
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spelling doaj.art-76b67c25adeb4eb19dbf62b0ba7a804a2022-12-22T03:16:19ZengWolters Kluwer Medknow PublicationsJournal of Medical Sciences1011-45642016-01-0136416216410.4103/1011-4564.188902Serous adenocarcinoma of endometrium coexistence with atypical polypoid adenomyoma in a postmenopausal woman: A rare caseChiu-Shih ChengYu-Chi WeiTang-Yuan ChuDah-Ching DingThis work describes a rare case of serous carcinoma coexistence with atypical polypoid adenomyoma (APA). A 55-year-old postmenopausal woman presented with intermittent vaginal bleeding for 1 year. Her Pap test exhibited atypical glandular cell and endometrial biopsy showed serous carcinoma. She underwent a staging surgery, and the histopathology revealed serous carcinoma with p53 mutation and coexistence with APA staged as FIGO Stage Ia, Grade 1. The patient recovered well postoperatively. APA lesion is generally benign, but it may progress in rare cases to adenocarcinoma, usually endometrioid type. This is the first case report regarding serous carcinoma coexistence with APA. Therefore, the patient with APA should always be closely followed up. Nevertheless, further study is stipulated to better understand the clinicopathological features of serous adenocarcinoma coexisting with APA.http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2016;volume=36;issue=4;spage=162;epage=164;aulast=ChengAtypical polypoid adenomyomaendometriummenopauseserous carcinoma
spellingShingle Chiu-Shih Cheng
Yu-Chi Wei
Tang-Yuan Chu
Dah-Ching Ding
Serous adenocarcinoma of endometrium coexistence with atypical polypoid adenomyoma in a postmenopausal woman: A rare case
Journal of Medical Sciences
Atypical polypoid adenomyoma
endometrium
menopause
serous carcinoma
title Serous adenocarcinoma of endometrium coexistence with atypical polypoid adenomyoma in a postmenopausal woman: A rare case
title_full Serous adenocarcinoma of endometrium coexistence with atypical polypoid adenomyoma in a postmenopausal woman: A rare case
title_fullStr Serous adenocarcinoma of endometrium coexistence with atypical polypoid adenomyoma in a postmenopausal woman: A rare case
title_full_unstemmed Serous adenocarcinoma of endometrium coexistence with atypical polypoid adenomyoma in a postmenopausal woman: A rare case
title_short Serous adenocarcinoma of endometrium coexistence with atypical polypoid adenomyoma in a postmenopausal woman: A rare case
title_sort serous adenocarcinoma of endometrium coexistence with atypical polypoid adenomyoma in a postmenopausal woman a rare case
topic Atypical polypoid adenomyoma
endometrium
menopause
serous carcinoma
url http://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2016;volume=36;issue=4;spage=162;epage=164;aulast=Cheng
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AT yuchiwei serousadenocarcinomaofendometriumcoexistencewithatypicalpolypoidadenomyomainapostmenopausalwomanararecase
AT tangyuanchu serousadenocarcinomaofendometriumcoexistencewithatypicalpolypoidadenomyomainapostmenopausalwomanararecase
AT dahchingding serousadenocarcinomaofendometriumcoexistencewithatypicalpolypoidadenomyomainapostmenopausalwomanararecase