Structural basis for gating mechanism of the human sodium-potassium pump
Through cryo-EM analysis, here authors reveal conformational rearrangements that are critical for the gating mechanism of the human alpha3 Na+/K+−ATPase
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-32990-x |
| _version_ | 1798003050531520512 |
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| author | Phong T. Nguyen Christine Deisl Michael Fine Trevor S. Tippetts Emiko Uchikawa Xiao-chen Bai Beth Levine |
| author_facet | Phong T. Nguyen Christine Deisl Michael Fine Trevor S. Tippetts Emiko Uchikawa Xiao-chen Bai Beth Levine |
| author_sort | Phong T. Nguyen |
| collection | DOAJ |
| description | Through cryo-EM analysis, here authors reveal conformational rearrangements that are critical for the gating mechanism of the human alpha3 Na+/K+−ATPase |
| first_indexed | 2024-04-11T12:01:52Z |
| format | Article |
| id | doaj.art-76b7117e2923402c8fc3c834dd1be515 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T12:01:52Z |
| publishDate | 2022-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-76b7117e2923402c8fc3c834dd1be5152022-12-22T04:24:50ZengNature PortfolioNature Communications2041-17232022-09-0113111210.1038/s41467-022-32990-xStructural basis for gating mechanism of the human sodium-potassium pumpPhong T. Nguyen0Christine Deisl1Michael Fine2Trevor S. Tippetts3Emiko Uchikawa4Xiao-chen Bai5Beth Levine6Howard Hughes Medical Institute and Department of Internal Medicine, University of Texas Southwestern Medical CenterDepartment of Physiology, University of Texas Southwestern Medical CenterDepartment of Physiology, University of Texas Southwestern Medical CenterChildren’s Research Institute, University of Texas Southwestern Medical CenterDepartment of Biophysics, University of Texas Southwestern Medical CenterDepartment of Biophysics, University of Texas Southwestern Medical CenterHoward Hughes Medical Institute and Department of Internal Medicine, University of Texas Southwestern Medical CenterThrough cryo-EM analysis, here authors reveal conformational rearrangements that are critical for the gating mechanism of the human alpha3 Na+/K+−ATPasehttps://doi.org/10.1038/s41467-022-32990-x |
| spellingShingle | Phong T. Nguyen Christine Deisl Michael Fine Trevor S. Tippetts Emiko Uchikawa Xiao-chen Bai Beth Levine Structural basis for gating mechanism of the human sodium-potassium pump Nature Communications |
| title | Structural basis for gating mechanism of the human sodium-potassium pump |
| title_full | Structural basis for gating mechanism of the human sodium-potassium pump |
| title_fullStr | Structural basis for gating mechanism of the human sodium-potassium pump |
| title_full_unstemmed | Structural basis for gating mechanism of the human sodium-potassium pump |
| title_short | Structural basis for gating mechanism of the human sodium-potassium pump |
| title_sort | structural basis for gating mechanism of the human sodium potassium pump |
| url | https://doi.org/10.1038/s41467-022-32990-x |
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