Superior Specimen and Diagnostic Accuracy with Endoscopic Ultrasound-Guided Liver Biopsies Using 19-Gauge versus 22-Gauge Core Needles
Background/Aims Endoscopic ultrasound-guided liver biopsy (EUS-LB) is an effective and safe method of procuring liver tissue. The aims of this study were to assess and compare the outcomes and tissue adequacy of a single-pass, single-actuation, wet suction technique between 19 G and 22 G needles in...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Society of Gastrointestinal Endoscopy
2021-09-01
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| Series: | Clinical Endoscopy |
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| Online Access: | http://www.e-ce.org/upload/pdf/ce-2020-212.pdf |
| _version_ | 1797428939538300928 |
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| author | Rucha M. Shah Jason Schmidt Elizabeth John Sheila Rastegari Priyanka Acharya Prashant Kedia |
| author_facet | Rucha M. Shah Jason Schmidt Elizabeth John Sheila Rastegari Priyanka Acharya Prashant Kedia |
| author_sort | Rucha M. Shah |
| collection | DOAJ |
| description | Background/Aims Endoscopic ultrasound-guided liver biopsy (EUS-LB) is an effective and safe method of procuring liver tissue. The aims of this study were to assess and compare the outcomes and tissue adequacy of a single-pass, single-actuation, wet suction technique between 19 G and 22 G needles in patients undergoing EUS-LB. Methods We performed a prospective case series study of 20 patients undergoing EUS-LB at a single center between September 2017 and April 2020. The primary objective was to evaluate differences in sample adequacy via a single actuation wet suction technique between a 19 G core needle and a 22 G core needle. Adequacy was gauged by cumulative core biopsy length and the number of portal tracts visualized. Results The 19 G needle provided a longer core length (2.5 cm vs. 1.2 cm, p<0.0001), more complete portal tracts (5.8 vs. 1.7, p<0.0001), more total tracts (8.8 vs. 3, p<0.0001), and a longer, intact, fragment length (0.75 cm vs. 0.32 cm, p<0.0006). The 19 G needle was superior in providing adequate (60% vs. 5%, p<0.001) and diagnostic pathologic samples (85% vs. 10%, p<0.001). Conclusions A single-pass, single-actuation, wet suction technique using a 19 G needle is superior to that using a 22 G needle for tissue acquisition and sample adequacy in EUS-LB. |
| first_indexed | 2024-03-09T09:06:04Z |
| format | Article |
| id | doaj.art-76b9eba55e7746838cd3d543f8be24bc |
| institution | Directory Open Access Journal |
| issn | 2234-2400 2234-2443 |
| language | English |
| last_indexed | 2024-03-09T09:06:04Z |
| publishDate | 2021-09-01 |
| publisher | Korean Society of Gastrointestinal Endoscopy |
| record_format | Article |
| series | Clinical Endoscopy |
| spelling | doaj.art-76b9eba55e7746838cd3d543f8be24bc2023-12-02T10:23:23ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432021-09-0154573974410.5946/ce.2020.2127426Superior Specimen and Diagnostic Accuracy with Endoscopic Ultrasound-Guided Liver Biopsies Using 19-Gauge versus 22-Gauge Core NeedlesRucha M. Shah0Jason Schmidt1Elizabeth John2Sheila Rastegari3Priyanka Acharya4Prashant Kedia5 Department of Gastroenterology, Methodist Dallas Medical Center, Dallas, TX, USA Department of Pathology, Methodist Dallas Medical Center, Dallas, TX, USA Department of Gastroenterology, Methodist Dallas Medical Center, Dallas, TX, USA Department of Internal Medicine, Methodist Dallas Medical Center, Dallas, TX, USA Methodist Health System Clinical Research Institute, Methodist Dallas Medical Center, Dallas, TX, USA Department of Gastroenterology, Methodist Dallas Medical Center, Dallas, TX, USABackground/Aims Endoscopic ultrasound-guided liver biopsy (EUS-LB) is an effective and safe method of procuring liver tissue. The aims of this study were to assess and compare the outcomes and tissue adequacy of a single-pass, single-actuation, wet suction technique between 19 G and 22 G needles in patients undergoing EUS-LB. Methods We performed a prospective case series study of 20 patients undergoing EUS-LB at a single center between September 2017 and April 2020. The primary objective was to evaluate differences in sample adequacy via a single actuation wet suction technique between a 19 G core needle and a 22 G core needle. Adequacy was gauged by cumulative core biopsy length and the number of portal tracts visualized. Results The 19 G needle provided a longer core length (2.5 cm vs. 1.2 cm, p<0.0001), more complete portal tracts (5.8 vs. 1.7, p<0.0001), more total tracts (8.8 vs. 3, p<0.0001), and a longer, intact, fragment length (0.75 cm vs. 0.32 cm, p<0.0006). The 19 G needle was superior in providing adequate (60% vs. 5%, p<0.001) and diagnostic pathologic samples (85% vs. 10%, p<0.001). Conclusions A single-pass, single-actuation, wet suction technique using a 19 G needle is superior to that using a 22 G needle for tissue acquisition and sample adequacy in EUS-LB.http://www.e-ce.org/upload/pdf/ce-2020-212.pdf19 g fnbendoscopic ultrasound-guided liver biopsyliver biopsy |
| spellingShingle | Rucha M. Shah Jason Schmidt Elizabeth John Sheila Rastegari Priyanka Acharya Prashant Kedia Superior Specimen and Diagnostic Accuracy with Endoscopic Ultrasound-Guided Liver Biopsies Using 19-Gauge versus 22-Gauge Core Needles Clinical Endoscopy 19 g fnb endoscopic ultrasound-guided liver biopsy liver biopsy |
| title | Superior Specimen and Diagnostic Accuracy with Endoscopic Ultrasound-Guided Liver Biopsies Using 19-Gauge versus 22-Gauge Core Needles |
| title_full | Superior Specimen and Diagnostic Accuracy with Endoscopic Ultrasound-Guided Liver Biopsies Using 19-Gauge versus 22-Gauge Core Needles |
| title_fullStr | Superior Specimen and Diagnostic Accuracy with Endoscopic Ultrasound-Guided Liver Biopsies Using 19-Gauge versus 22-Gauge Core Needles |
| title_full_unstemmed | Superior Specimen and Diagnostic Accuracy with Endoscopic Ultrasound-Guided Liver Biopsies Using 19-Gauge versus 22-Gauge Core Needles |
| title_short | Superior Specimen and Diagnostic Accuracy with Endoscopic Ultrasound-Guided Liver Biopsies Using 19-Gauge versus 22-Gauge Core Needles |
| title_sort | superior specimen and diagnostic accuracy with endoscopic ultrasound guided liver biopsies using 19 gauge versus 22 gauge core needles |
| topic | 19 g fnb endoscopic ultrasound-guided liver biopsy liver biopsy |
| url | http://www.e-ce.org/upload/pdf/ce-2020-212.pdf |
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