Reversal of ciliary mechanisms of disassembly rescues olfactory dysfunction in ciliopathies

Reversal of ciliary mechanisms of disassembly rescues olfactory dysfunction in ciliopathies

Ciliopathies are a class of genetic diseases resulting in cilia dysfunction in multiple organ systems, including the olfactory system. Currently, there are no available curative treatments for olfactory dysfunction and other symptoms in ciliopathies. The loss or shortening of olfactory cilia, as see...

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Bibliographic Details
Main Authors: Chao Xie, Julien C. Habif, Kirill Ukhanov, Cedric R. Uytingco, Lian Zhang, Robert J. Campbell, Jeffrey R. Martens
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-08-01
Series:JCI Insight
Subjects:
Cell biology
Genetics
Online Access:https://doi.org/10.1172/jci.insight.158736

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