Retrospective Comparison of Laparoscopic versus Open Radical Hysterectomy for Early-Stage Cervical Cancer in a Single Tertiary Care Institution from Lithuania between 2009 and 2019
<i>Background and Objectives</i>: A great debate within the academic arena was evoked by the LACC study, giving rise to doubt regarding the oncological outcomes of the laparoscopic approach for early-stage cervical cancer. This encouraged us to conduct a retrospective analysis of CC trea...
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MDPI AG
2022-04-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/58/4/553 |
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| author | Danuta Vasilevska Dominika Vasilevska Andrzej Semczuk Vilius Rudaitis |
| author_facet | Danuta Vasilevska Dominika Vasilevska Andrzej Semczuk Vilius Rudaitis |
| author_sort | Danuta Vasilevska |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: A great debate within the academic arena was evoked by the LACC study, giving rise to doubt regarding the oncological outcomes of the laparoscopic approach for early-stage cervical cancer. This encouraged us to conduct a retrospective analysis of CC treatment surgical approaches applied to the patients at tertiary level Vilnius University Hospital Santaros Clinics, Vilnius, Lithuania, between 2009 and 2019. <i>Materials and Methods</i>: The retrospective study was carried out to evaluate the outcomes after 28 laparoscopic and 62 laparotomic radical hysterectomies for early cervical cancer in a single tertiary care institution performed during the period 2009–2019. For statistical analysis of patients’ parameters, SPSS v. 17.0 was applied, together with the Kaplan–Meier method with a long-rank test and the Cox proportional hazard regression model used for bi-variate analysis determining OS outcomes between MIS and open-surgery groups. <i>Results</i>: After computing data with the Cox regression model, there was no significant difference of the 36-months overall survival between laparoscopy and laparotomy groups, as opposed to the LACC study. <i>Conclusions</i>: Our tertiary institution faces a considerable challenge, and we acknowledge the limitations of the study and also feel a responsibility to follow the latest guidelines. Currently, it appears that the most substantial attention should be focused on the cessation of uterine manipulator use as well as laparoscopic technique learning curves. |
| first_indexed | 2024-03-09T04:24:54Z |
| format | Article |
| id | doaj.art-76baff9a512c4cd59918f0dcd3be2486 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T04:24:54Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-76baff9a512c4cd59918f0dcd3be24862023-12-03T13:41:28ZengMDPI AGMedicina1010-660X1648-91442022-04-0158455310.3390/medicina58040553Retrospective Comparison of Laparoscopic versus Open Radical Hysterectomy for Early-Stage Cervical Cancer in a Single Tertiary Care Institution from Lithuania between 2009 and 2019Danuta Vasilevska0Dominika Vasilevska1Andrzej Semczuk2Vilius Rudaitis3Department of Gynecology, Vilnius University Hospital Santaros Clinics, 08661 Vilnius, LithuaniaFaculty of Medicine, Vilnius University, 03101 Vilnius, LithuaniaII<sup>ND</sup> Department of Gynecology, Lublin Medical University, 20090 Lublin, PolandFaculty of Medicine, Vilnius University, 03101 Vilnius, Lithuania<i>Background and Objectives</i>: A great debate within the academic arena was evoked by the LACC study, giving rise to doubt regarding the oncological outcomes of the laparoscopic approach for early-stage cervical cancer. This encouraged us to conduct a retrospective analysis of CC treatment surgical approaches applied to the patients at tertiary level Vilnius University Hospital Santaros Clinics, Vilnius, Lithuania, between 2009 and 2019. <i>Materials and Methods</i>: The retrospective study was carried out to evaluate the outcomes after 28 laparoscopic and 62 laparotomic radical hysterectomies for early cervical cancer in a single tertiary care institution performed during the period 2009–2019. For statistical analysis of patients’ parameters, SPSS v. 17.0 was applied, together with the Kaplan–Meier method with a long-rank test and the Cox proportional hazard regression model used for bi-variate analysis determining OS outcomes between MIS and open-surgery groups. <i>Results</i>: After computing data with the Cox regression model, there was no significant difference of the 36-months overall survival between laparoscopy and laparotomy groups, as opposed to the LACC study. <i>Conclusions</i>: Our tertiary institution faces a considerable challenge, and we acknowledge the limitations of the study and also feel a responsibility to follow the latest guidelines. Currently, it appears that the most substantial attention should be focused on the cessation of uterine manipulator use as well as laparoscopic technique learning curves.https://www.mdpi.com/1648-9144/58/4/553early-stage cervical cancerLACC studyradical hysterectomysurgical gynecological oncology |
| spellingShingle | Danuta Vasilevska Dominika Vasilevska Andrzej Semczuk Vilius Rudaitis Retrospective Comparison of Laparoscopic versus Open Radical Hysterectomy for Early-Stage Cervical Cancer in a Single Tertiary Care Institution from Lithuania between 2009 and 2019 Medicina early-stage cervical cancer LACC study radical hysterectomy surgical gynecological oncology |
| title | Retrospective Comparison of Laparoscopic versus Open Radical Hysterectomy for Early-Stage Cervical Cancer in a Single Tertiary Care Institution from Lithuania between 2009 and 2019 |
| title_full | Retrospective Comparison of Laparoscopic versus Open Radical Hysterectomy for Early-Stage Cervical Cancer in a Single Tertiary Care Institution from Lithuania between 2009 and 2019 |
| title_fullStr | Retrospective Comparison of Laparoscopic versus Open Radical Hysterectomy for Early-Stage Cervical Cancer in a Single Tertiary Care Institution from Lithuania between 2009 and 2019 |
| title_full_unstemmed | Retrospective Comparison of Laparoscopic versus Open Radical Hysterectomy for Early-Stage Cervical Cancer in a Single Tertiary Care Institution from Lithuania between 2009 and 2019 |
| title_short | Retrospective Comparison of Laparoscopic versus Open Radical Hysterectomy for Early-Stage Cervical Cancer in a Single Tertiary Care Institution from Lithuania between 2009 and 2019 |
| title_sort | retrospective comparison of laparoscopic versus open radical hysterectomy for early stage cervical cancer in a single tertiary care institution from lithuania between 2009 and 2019 |
| topic | early-stage cervical cancer LACC study radical hysterectomy surgical gynecological oncology |
| url | https://www.mdpi.com/1648-9144/58/4/553 |
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