Proximal myopathy in lacto-vegetarian Asian patients responding to Vitamin D and calcium supplement therapy - two case reports and review of the literature

<p>Abstract</p> <p>Introduction</p> <p>Severe proximal myopathy can occasionally be the first presenting complaint of patients with osteomalacia. This may lead to investigations and misdiagnosis of a neuromuscular disease, rather than a metabolic bone disease.</p>...

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Main Authors: Sreenan Seamus, Barry Maurice, Thabit Hood, Smith Diarmuid
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Journal of Medical Case Reports
Online Access:http://www.jmedicalcasereports.com/content/5/1/178
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author Sreenan Seamus
Barry Maurice
Thabit Hood
Smith Diarmuid
author_facet Sreenan Seamus
Barry Maurice
Thabit Hood
Smith Diarmuid
author_sort Sreenan Seamus
collection DOAJ
description <p>Abstract</p> <p>Introduction</p> <p>Severe proximal myopathy can occasionally be the first presenting complaint of patients with osteomalacia. This may lead to investigations and misdiagnosis of a neuromuscular disease, rather than a metabolic bone disease.</p> <p>Case presentations</p> <p>We present here two cases of severe proximal myopathy in patients who were both of South Asian origin and lacto-vegetarians: a 31-year-old Indian man and a 34-year-old Indian woman. In both cases, their clinical symptoms fully resolved following vitamin D and calcium replacement therapy. These patients were at risk of osteomalacia due to their dietary intake and ethnicity. The role of dietary intake and sunlight exposure in the development of osteomalacia in certain ethnic groups living in Western Europe is reviewed here.</p> <p>Conclusion</p> <p>These two cases emphasize the importance of recognizing osteomalacia in at-risk individuals, as the condition is reversible and easily treated with vitamin D and calcium supplementation. It may also help avoid prolonged and unnecessary investigations of these patients.</p>
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spelling doaj.art-76bdd38ef79e44b590eb41b1ac98388f2022-12-22T02:13:13ZengBMCJournal of Medical Case Reports1752-19472011-05-015117810.1186/1752-1947-5-178Proximal myopathy in lacto-vegetarian Asian patients responding to Vitamin D and calcium supplement therapy - two case reports and review of the literatureSreenan SeamusBarry MauriceThabit HoodSmith Diarmuid<p>Abstract</p> <p>Introduction</p> <p>Severe proximal myopathy can occasionally be the first presenting complaint of patients with osteomalacia. This may lead to investigations and misdiagnosis of a neuromuscular disease, rather than a metabolic bone disease.</p> <p>Case presentations</p> <p>We present here two cases of severe proximal myopathy in patients who were both of South Asian origin and lacto-vegetarians: a 31-year-old Indian man and a 34-year-old Indian woman. In both cases, their clinical symptoms fully resolved following vitamin D and calcium replacement therapy. These patients were at risk of osteomalacia due to their dietary intake and ethnicity. The role of dietary intake and sunlight exposure in the development of osteomalacia in certain ethnic groups living in Western Europe is reviewed here.</p> <p>Conclusion</p> <p>These two cases emphasize the importance of recognizing osteomalacia in at-risk individuals, as the condition is reversible and easily treated with vitamin D and calcium supplementation. It may also help avoid prolonged and unnecessary investigations of these patients.</p>http://www.jmedicalcasereports.com/content/5/1/178
spellingShingle Sreenan Seamus
Barry Maurice
Thabit Hood
Smith Diarmuid
Proximal myopathy in lacto-vegetarian Asian patients responding to Vitamin D and calcium supplement therapy - two case reports and review of the literature
Journal of Medical Case Reports
title Proximal myopathy in lacto-vegetarian Asian patients responding to Vitamin D and calcium supplement therapy - two case reports and review of the literature
title_full Proximal myopathy in lacto-vegetarian Asian patients responding to Vitamin D and calcium supplement therapy - two case reports and review of the literature
title_fullStr Proximal myopathy in lacto-vegetarian Asian patients responding to Vitamin D and calcium supplement therapy - two case reports and review of the literature
title_full_unstemmed Proximal myopathy in lacto-vegetarian Asian patients responding to Vitamin D and calcium supplement therapy - two case reports and review of the literature
title_short Proximal myopathy in lacto-vegetarian Asian patients responding to Vitamin D and calcium supplement therapy - two case reports and review of the literature
title_sort proximal myopathy in lacto vegetarian asian patients responding to vitamin d and calcium supplement therapy two case reports and review of the literature
url http://www.jmedicalcasereports.com/content/5/1/178
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