Predicting Accurate Lead Structures for Screening Molecular Libraries: A Quantum Crystallographic Approach
Optimization of lead structures is crucial for drug discovery. However, the accuracy of such a prediction using the traditional molecular docking approach remains a major concern. Our study demonstrates that the employment of quantum crystallographic approach-counterpoise corrected kernel energy met...
Main Authors: | Suman Kumar Mandal, Parthapratim Munshi |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/9/2605 |
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