Comparative Analysis of 60Co and 192Ir Sources in High Dose Rate Brachytherapy for Cervical Cancer
High-dose-rate (HDR) brachytherapy (BT) is an essential treatment for cervical cancer, one of the most prevalent gynecological malignant tumors. In HDR BT, high radiation doses can be delivered to the tumor target with the minimum radiation doses to organs at risk. Despite the wide use of the small...
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| Format: | Article |
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MDPI AG
2022-09-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/14/19/4749 |
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| author | Aiping Wen Xianliang Wang Bingjie Wang Chuanjun Yan Jingyue Luo Pei Wang Jie Li |
| author_facet | Aiping Wen Xianliang Wang Bingjie Wang Chuanjun Yan Jingyue Luo Pei Wang Jie Li |
| author_sort | Aiping Wen |
| collection | DOAJ |
| description | High-dose-rate (HDR) brachytherapy (BT) is an essential treatment for cervical cancer, one of the most prevalent gynecological malignant tumors. In HDR BT, high radiation doses can be delivered to the tumor target with the minimum radiation doses to organs at risk. Despite the wide use of the small HDR 192Ir source, as the technique has improved, the HDR 60Co source, which has the same miniaturized geometry, has also been produced and put into clinical practice. Compared with 192Ir (74 days), 60Co has a longer half-life (5.3 years), which gives it a great economic advantage for developing nations. The aim of the study was to compare 60Co and 192Ir sources for HDR BT in terms of both dosimetry and clinical treatment. The results of reports published on the use of HDR BT for cervical cancer over the past few years as well as our own research show that this treatment is safe and it is feasible to use 60Co as an alternative source. |
| first_indexed | 2024-03-09T21:56:48Z |
| format | Article |
| id | doaj.art-76c1391db1d84b5f85b4477365571db4 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-09T21:56:48Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-76c1391db1d84b5f85b4477365571db42023-11-23T19:55:58ZengMDPI AGCancers2072-66942022-09-011419474910.3390/cancers14194749Comparative Analysis of 60Co and 192Ir Sources in High Dose Rate Brachytherapy for Cervical CancerAiping Wen0Xianliang Wang1Bingjie Wang2Chuanjun Yan3Jingyue Luo4Pei Wang5Jie Li6School of Medicine, University of Electronic Science and Technology of China, Chengdu 610054, ChinaSchool of Medicine, University of Electronic Science and Technology of China, Chengdu 610054, ChinaDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hongkong 999077, ChinaDepartment of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, ChinaSchool of Medicine, University of Electronic Science and Technology of China, Chengdu 610054, ChinaSchool of Medicine, University of Electronic Science and Technology of China, Chengdu 610054, ChinaSchool of Medicine, University of Electronic Science and Technology of China, Chengdu 610054, ChinaHigh-dose-rate (HDR) brachytherapy (BT) is an essential treatment for cervical cancer, one of the most prevalent gynecological malignant tumors. In HDR BT, high radiation doses can be delivered to the tumor target with the minimum radiation doses to organs at risk. Despite the wide use of the small HDR 192Ir source, as the technique has improved, the HDR 60Co source, which has the same miniaturized geometry, has also been produced and put into clinical practice. Compared with 192Ir (74 days), 60Co has a longer half-life (5.3 years), which gives it a great economic advantage for developing nations. The aim of the study was to compare 60Co and 192Ir sources for HDR BT in terms of both dosimetry and clinical treatment. The results of reports published on the use of HDR BT for cervical cancer over the past few years as well as our own research show that this treatment is safe and it is feasible to use 60Co as an alternative source.https://www.mdpi.com/2072-6694/14/19/474960Co192Ircervical cancerhigh-dose-rate brachytherapy |
| spellingShingle | Aiping Wen Xianliang Wang Bingjie Wang Chuanjun Yan Jingyue Luo Pei Wang Jie Li Comparative Analysis of 60Co and 192Ir Sources in High Dose Rate Brachytherapy for Cervical Cancer Cancers 60Co 192Ir cervical cancer high-dose-rate brachytherapy |
| title | Comparative Analysis of 60Co and 192Ir Sources in High Dose Rate Brachytherapy for Cervical Cancer |
| title_full | Comparative Analysis of 60Co and 192Ir Sources in High Dose Rate Brachytherapy for Cervical Cancer |
| title_fullStr | Comparative Analysis of 60Co and 192Ir Sources in High Dose Rate Brachytherapy for Cervical Cancer |
| title_full_unstemmed | Comparative Analysis of 60Co and 192Ir Sources in High Dose Rate Brachytherapy for Cervical Cancer |
| title_short | Comparative Analysis of 60Co and 192Ir Sources in High Dose Rate Brachytherapy for Cervical Cancer |
| title_sort | comparative analysis of 60co and 192ir sources in high dose rate brachytherapy for cervical cancer |
| topic | 60Co 192Ir cervical cancer high-dose-rate brachytherapy |
| url | https://www.mdpi.com/2072-6694/14/19/4749 |
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