Tests for predicting complications of pre-eclampsia: A protocol for systematic reviews
<p>Abstract</p> <p>Background</p> <p>Pre-eclampsia is associated with several complications. Early prediction of complications and timely management is needed for clinical care of these patients to avert fetal and maternal mortality and morbidity. There is a need to ide...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-08-01
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| Series: | BMC Pregnancy and Childbirth |
| Online Access: | http://www.biomedcentral.com/1471-2393/8/38 |
| _version_ | 1818824351291539456 |
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| author | O'Brien Shaughn O'Mahony Fidelma Sharp Steve Coomarasamy Arri Thangaratinam Shakila Ismail Khaled MK Khan Khalid S |
| author_facet | O'Brien Shaughn O'Mahony Fidelma Sharp Steve Coomarasamy Arri Thangaratinam Shakila Ismail Khaled MK Khan Khalid S |
| author_sort | O'Brien Shaughn |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Pre-eclampsia is associated with several complications. Early prediction of complications and timely management is needed for clinical care of these patients to avert fetal and maternal mortality and morbidity. There is a need to identify best testing strategies in pre eclampsia to identify the women at increased risk of complications. We aim to determine the accuracy of various tests to predict complications of pre-eclampsia by systematic quantitative reviews.</p> <p>Method</p> <p>We performed extensive search in MEDLINE (1951–2004), EMBASE (1974–2004) and also will also include manual searches of bibliographies of primary and review articles. An initial search has revealed 19500 citations. Two reviewers will independently select studies and extract data on study characteristics, quality and accuracy. Accuracy data will be used to construct 2 × 2 tables. Data synthesis will involve assessment for heterogeneity and appropriately pooling of results to produce summary Receiver Operating Characteristics (ROC) curve and summary likelihood ratios.</p> <p>Discussion</p> <p>This review will generate predictive information and integrate that with therapeutic effectiveness to determine the absolute benefit and harm of available therapy in reducing complications in women with pre-eclampsia.</p> |
| first_indexed | 2024-12-18T23:54:29Z |
| format | Article |
| id | doaj.art-76c2f406963042ea878ed1980b25aca7 |
| institution | Directory Open Access Journal |
| issn | 1471-2393 |
| language | English |
| last_indexed | 2024-12-18T23:54:29Z |
| publishDate | 2008-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj.art-76c2f406963042ea878ed1980b25aca72022-12-21T20:46:45ZengBMCBMC Pregnancy and Childbirth1471-23932008-08-01813810.1186/1471-2393-8-38Tests for predicting complications of pre-eclampsia: A protocol for systematic reviewsO'Brien ShaughnO'Mahony FidelmaSharp SteveCoomarasamy ArriThangaratinam ShakilaIsmail Khaled MKKhan Khalid S<p>Abstract</p> <p>Background</p> <p>Pre-eclampsia is associated with several complications. Early prediction of complications and timely management is needed for clinical care of these patients to avert fetal and maternal mortality and morbidity. There is a need to identify best testing strategies in pre eclampsia to identify the women at increased risk of complications. We aim to determine the accuracy of various tests to predict complications of pre-eclampsia by systematic quantitative reviews.</p> <p>Method</p> <p>We performed extensive search in MEDLINE (1951–2004), EMBASE (1974–2004) and also will also include manual searches of bibliographies of primary and review articles. An initial search has revealed 19500 citations. Two reviewers will independently select studies and extract data on study characteristics, quality and accuracy. Accuracy data will be used to construct 2 × 2 tables. Data synthesis will involve assessment for heterogeneity and appropriately pooling of results to produce summary Receiver Operating Characteristics (ROC) curve and summary likelihood ratios.</p> <p>Discussion</p> <p>This review will generate predictive information and integrate that with therapeutic effectiveness to determine the absolute benefit and harm of available therapy in reducing complications in women with pre-eclampsia.</p>http://www.biomedcentral.com/1471-2393/8/38 |
| spellingShingle | O'Brien Shaughn O'Mahony Fidelma Sharp Steve Coomarasamy Arri Thangaratinam Shakila Ismail Khaled MK Khan Khalid S Tests for predicting complications of pre-eclampsia: A protocol for systematic reviews BMC Pregnancy and Childbirth |
| title | Tests for predicting complications of pre-eclampsia: A protocol for systematic reviews |
| title_full | Tests for predicting complications of pre-eclampsia: A protocol for systematic reviews |
| title_fullStr | Tests for predicting complications of pre-eclampsia: A protocol for systematic reviews |
| title_full_unstemmed | Tests for predicting complications of pre-eclampsia: A protocol for systematic reviews |
| title_short | Tests for predicting complications of pre-eclampsia: A protocol for systematic reviews |
| title_sort | tests for predicting complications of pre eclampsia a protocol for systematic reviews |
| url | http://www.biomedcentral.com/1471-2393/8/38 |
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