Quantitative prediction of ensemble dynamics, shapes and contact propensities of intrinsically disordered proteins.
Intrinsically disordered proteins (IDPs) are highly dynamic systems that play an important role in cell signaling processes and their misfunction often causes human disease. Proper understanding of IDP function not only requires the realistic characterization of their three-dimensional conformationa...
Main Authors: | Lei Yu, Rafael Brüschweiler |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-09-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1010036 |
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