Evaluation of Oxidative Stress and some Biochemical Parameters in Normal Pregnant Women
Pregnancy is associated with many metabolic changes in normal pregnant woman, this leads to change in physiological, biochemical, and hematological parameters drastically. The test subjects were selected among those attending to Maternity Teaching Hospital in Erbil Governorate between March 2017 and...
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| Format: | Article |
| Language: | English |
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Koya University
2020-02-01
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| Series: | ARO-The Scientific Journal of Koya University |
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| Online Access: | http://aro.koyauniversity.org/article/view/541 |
| _version_ | 1797707132829696000 |
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| author | Musher I. Kakey Kamaran K. Abdoulrahman Gulbahar R. Uthman |
| author_facet | Musher I. Kakey Kamaran K. Abdoulrahman Gulbahar R. Uthman |
| author_sort | Musher I. Kakey |
| collection | DOAJ |
| description | Pregnancy is associated with many metabolic changes in normal pregnant woman, this leads to change in physiological, biochemical, and hematological parameters drastically. The test subjects were selected among those attending to Maternity Teaching Hospital in Erbil Governorate between March 2017 and August 2017. Four groups of individuals were included in this study, 230 pregnant women divided into three groups (Group 1 first trimester, Group 2 second trimester, and Group 3 third trimester) and Group 4 contained 90 nonpregnant women as control. Full automatic chemical analyzer (Cobas C311, Germany) was used to determine the biochemical parameters. The EL ×800 Absorbance Microplate Reader from BioTek (USA) instruments is used to measure the activity of superoxide dismutase (SOD), catalase (CAT), and malondialdehyde (MDA) in serum. The results of this study showed a significant increase in serum albumin, glucose, total bilirubin, direct bilirubin, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, creatinine, urea, cholesterol, low-density lipoprotein, and MDA in pregnant women as compared to the control group, also show significant decrease in high-density lipoprotein (HDL) level, SOD activity, and CAT activity in pregnant women as compared to nonpregnant women, and nonsignificant difference in uric acid, and HDL. |
| first_indexed | 2024-03-12T06:02:51Z |
| format | Article |
| id | doaj.art-76c99c73b1924c219e6c4b776fa66311 |
| institution | Directory Open Access Journal |
| issn | 2410-9355 2307-549X |
| language | English |
| last_indexed | 2024-03-12T06:02:51Z |
| publishDate | 2020-02-01 |
| publisher | Koya University |
| record_format | Article |
| series | ARO-The Scientific Journal of Koya University |
| spelling | doaj.art-76c99c73b1924c219e6c4b776fa663112023-09-03T04:00:58ZengKoya UniversityARO-The Scientific Journal of Koya University2410-93552307-549X2020-02-0181172310.14500/aro.10541122Evaluation of Oxidative Stress and some Biochemical Parameters in Normal Pregnant WomenMusher I. Kakey0Kamaran K. Abdoulrahman1Gulbahar R. Uthman2Department of Chemistry, Faculty of Science and Health, Koya University, Koya KOY45, Kurdistan RegionDepartment of Chemistry, College of Science, Salahaddin University, Erbil, Kurdistan RegionDepartment of Chemistry, College of Science, Salahaddin University, Erbil, Kurdistan RegionPregnancy is associated with many metabolic changes in normal pregnant woman, this leads to change in physiological, biochemical, and hematological parameters drastically. The test subjects were selected among those attending to Maternity Teaching Hospital in Erbil Governorate between March 2017 and August 2017. Four groups of individuals were included in this study, 230 pregnant women divided into three groups (Group 1 first trimester, Group 2 second trimester, and Group 3 third trimester) and Group 4 contained 90 nonpregnant women as control. Full automatic chemical analyzer (Cobas C311, Germany) was used to determine the biochemical parameters. The EL ×800 Absorbance Microplate Reader from BioTek (USA) instruments is used to measure the activity of superoxide dismutase (SOD), catalase (CAT), and malondialdehyde (MDA) in serum. The results of this study showed a significant increase in serum albumin, glucose, total bilirubin, direct bilirubin, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, creatinine, urea, cholesterol, low-density lipoprotein, and MDA in pregnant women as compared to the control group, also show significant decrease in high-density lipoprotein (HDL) level, SOD activity, and CAT activity in pregnant women as compared to nonpregnant women, and nonsignificant difference in uric acid, and HDL.http://aro.koyauniversity.org/article/view/541pregnancyoxidative stressliver parameterslipid profileskidney function |
| spellingShingle | Musher I. Kakey Kamaran K. Abdoulrahman Gulbahar R. Uthman Evaluation of Oxidative Stress and some Biochemical Parameters in Normal Pregnant Women ARO-The Scientific Journal of Koya University pregnancy oxidative stress liver parameters lipid profiles kidney function |
| title | Evaluation of Oxidative Stress and some Biochemical Parameters in Normal Pregnant Women |
| title_full | Evaluation of Oxidative Stress and some Biochemical Parameters in Normal Pregnant Women |
| title_fullStr | Evaluation of Oxidative Stress and some Biochemical Parameters in Normal Pregnant Women |
| title_full_unstemmed | Evaluation of Oxidative Stress and some Biochemical Parameters in Normal Pregnant Women |
| title_short | Evaluation of Oxidative Stress and some Biochemical Parameters in Normal Pregnant Women |
| title_sort | evaluation of oxidative stress and some biochemical parameters in normal pregnant women |
| topic | pregnancy oxidative stress liver parameters lipid profiles kidney function |
| url | http://aro.koyauniversity.org/article/view/541 |
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