Intramuscular pyrethroid with organophosphorus (cypermethrine 3% + quinolphos 20%) mixed poisoning, its clinical presentation and management
Organophosphorus compounds are absorbed by any route including intramuscular injection. Pyrethroid compounds are less toxic for human but in combination with organophosphates, its toxic effect potentiates due to inhibition of its metabolism. In this case report, a 40-year-old female patient presente...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=5;spage=2521;epage=2523;aulast=Nizami |
| _version_ | 1818962337540866048 |
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| author | Mohammad Firoz Nizami Chandra B Sharma Bhoopendra Singh Rishi T Guria |
| author_facet | Mohammad Firoz Nizami Chandra B Sharma Bhoopendra Singh Rishi T Guria |
| author_sort | Mohammad Firoz Nizami |
| collection | DOAJ |
| description | Organophosphorus compounds are absorbed by any route including intramuscular injection. Pyrethroid compounds are less toxic for human but in combination with organophosphates, its toxic effect potentiates due to inhibition of its metabolism. In this case report, a 40-year-old female patient presented with acute onset of pain abdomen, recurrent vomiting, and excessive salivation followed by altered mental status, on evaluation her clinical findings were suggestive of organophosphorus poisoning. Her treatment was started with injection atropine, anti-emetics, and adequate parenteral rehydration. After regaining consciousness, the patient confessed that she had taken herself intramuscular injection of pesticide which contained 3% cypermethrine plus 20% quinolphos. It was further confirmed by a very low level of plasma cholinesterase level. Intramuscular injection acted as a depot that leads to prolong intoxication and in the due course of illness, she also developed delayed onset intermediate syndrome that was managed appropriately. |
| first_indexed | 2024-12-20T12:27:43Z |
| format | Article |
| id | doaj.art-76cb8288cb58496ea4b9904907e835b1 |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-12-20T12:27:43Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-76cb8288cb58496ea4b9904907e835b12022-12-21T19:40:49ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632020-01-01952521252310.4103/jfmpc.jfmpc_16_20Intramuscular pyrethroid with organophosphorus (cypermethrine 3% + quinolphos 20%) mixed poisoning, its clinical presentation and managementMohammad Firoz NizamiChandra B SharmaBhoopendra SinghRishi T GuriaOrganophosphorus compounds are absorbed by any route including intramuscular injection. Pyrethroid compounds are less toxic for human but in combination with organophosphates, its toxic effect potentiates due to inhibition of its metabolism. In this case report, a 40-year-old female patient presented with acute onset of pain abdomen, recurrent vomiting, and excessive salivation followed by altered mental status, on evaluation her clinical findings were suggestive of organophosphorus poisoning. Her treatment was started with injection atropine, anti-emetics, and adequate parenteral rehydration. After regaining consciousness, the patient confessed that she had taken herself intramuscular injection of pesticide which contained 3% cypermethrine plus 20% quinolphos. It was further confirmed by a very low level of plasma cholinesterase level. Intramuscular injection acted as a depot that leads to prolong intoxication and in the due course of illness, she also developed delayed onset intermediate syndrome that was managed appropriately.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=5;spage=2521;epage=2523;aulast=Nizamicypermethrine poisoningintramuscularorganophosphate |
| spellingShingle | Mohammad Firoz Nizami Chandra B Sharma Bhoopendra Singh Rishi T Guria Intramuscular pyrethroid with organophosphorus (cypermethrine 3% + quinolphos 20%) mixed poisoning, its clinical presentation and management Journal of Family Medicine and Primary Care cypermethrine poisoning intramuscular organophosphate |
| title | Intramuscular pyrethroid with organophosphorus (cypermethrine 3% + quinolphos 20%) mixed poisoning, its clinical presentation and management |
| title_full | Intramuscular pyrethroid with organophosphorus (cypermethrine 3% + quinolphos 20%) mixed poisoning, its clinical presentation and management |
| title_fullStr | Intramuscular pyrethroid with organophosphorus (cypermethrine 3% + quinolphos 20%) mixed poisoning, its clinical presentation and management |
| title_full_unstemmed | Intramuscular pyrethroid with organophosphorus (cypermethrine 3% + quinolphos 20%) mixed poisoning, its clinical presentation and management |
| title_short | Intramuscular pyrethroid with organophosphorus (cypermethrine 3% + quinolphos 20%) mixed poisoning, its clinical presentation and management |
| title_sort | intramuscular pyrethroid with organophosphorus cypermethrine 3 quinolphos 20 mixed poisoning its clinical presentation and management |
| topic | cypermethrine poisoning intramuscular organophosphate |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=5;spage=2521;epage=2523;aulast=Nizami |
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