Deterrent Action of Acamprosate: A Case Report
Background: Among the three pharmacological agents available for alcohol de-addiction, acamprosate and naltrexone are considered anti-craving agents. Among these two, acamprosate is better tolerated, has low abuse potential, and is safe in overdose. But the mechanism of action of acamprosate still r...
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| Format: | Article |
| Language: | English |
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Kerman University of Medical Sciences
2019-12-01
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| Series: | Addiction and Health |
| Subjects: | |
| Online Access: | https://ahj.kmu.ac.ir/article_89570_4a68403a8c8f6b05ed165abfc652d130.pdf |
| _version_ | 1797681933648396288 |
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| author | MAMIDIPALLI SAI SPOORTHY Sanghamitra Godi Lokesh Kumar Singh |
| author_facet | MAMIDIPALLI SAI SPOORTHY Sanghamitra Godi Lokesh Kumar Singh |
| author_sort | MAMIDIPALLI SAI SPOORTHY |
| collection | DOAJ |
| description | Background: Among the three pharmacological agents available for alcohol de-addiction, acamprosate and naltrexone are considered anti-craving agents. Among these two, acamprosate is better tolerated, has low abuse potential, and is safe in overdose. But the mechanism of action of acamprosate still remains unclear. Case Report: This case report gives a description of a 46-year-old male patient diagnosed with alcohol dependence syndrome with prior admissions and failed treatments with naltrexone and baclofen. He developed skin reaction after relapsing with alcohol use while receiving acamprosate therapy. The severity of the adverse effects varied with the amount of alcohol consumed by the patient. This suggests the possibility of deterrent-like action of acamprosate in our patient. The symptoms reduced after abstinence from alcohol and the patient was continued on acamprosate and relapse prevention therapy (RPT). Conclusion: Clinicians should consider the possible deterrent effect of acamprosate and manage such patients accordingly. |
| first_indexed | 2024-03-11T23:52:11Z |
| format | Article |
| id | doaj.art-76cb88d79a7b4a9b9d6d16de7b0dc9ba |
| institution | Directory Open Access Journal |
| issn | 2008-4633 2008-8469 |
| language | English |
| last_indexed | 2024-03-11T23:52:11Z |
| publishDate | 2019-12-01 |
| publisher | Kerman University of Medical Sciences |
| record_format | Article |
| series | Addiction and Health |
| spelling | doaj.art-76cb88d79a7b4a9b9d6d16de7b0dc9ba2023-09-19T06:46:12ZengKerman University of Medical SciencesAddiction and Health2008-46332008-84692019-12-0111427628010.22122/ahj.v11i4.24889570Deterrent Action of Acamprosate: A Case ReportMAMIDIPALLI SAI SPOORTHY0Sanghamitra Godi1Lokesh Kumar Singh2Department of Psychiatry, All India Institute of Medical Sciences, Raipur, IndiaDepartment of Psychiatry, All India Institute of Medical Sciences, Raipur, IndiaDepartment of Psychiatry, All India Institute of Medical Sciences, Raipur, IndiaBackground: Among the three pharmacological agents available for alcohol de-addiction, acamprosate and naltrexone are considered anti-craving agents. Among these two, acamprosate is better tolerated, has low abuse potential, and is safe in overdose. But the mechanism of action of acamprosate still remains unclear. Case Report: This case report gives a description of a 46-year-old male patient diagnosed with alcohol dependence syndrome with prior admissions and failed treatments with naltrexone and baclofen. He developed skin reaction after relapsing with alcohol use while receiving acamprosate therapy. The severity of the adverse effects varied with the amount of alcohol consumed by the patient. This suggests the possibility of deterrent-like action of acamprosate in our patient. The symptoms reduced after abstinence from alcohol and the patient was continued on acamprosate and relapse prevention therapy (RPT). Conclusion: Clinicians should consider the possible deterrent effect of acamprosate and manage such patients accordingly.https://ahj.kmu.ac.ir/article_89570_4a68403a8c8f6b05ed165abfc652d130.pdfadverse effectsacamprosateurticaria |
| spellingShingle | MAMIDIPALLI SAI SPOORTHY Sanghamitra Godi Lokesh Kumar Singh Deterrent Action of Acamprosate: A Case Report Addiction and Health adverse effects acamprosate urticaria |
| title | Deterrent Action of Acamprosate: A Case Report |
| title_full | Deterrent Action of Acamprosate: A Case Report |
| title_fullStr | Deterrent Action of Acamprosate: A Case Report |
| title_full_unstemmed | Deterrent Action of Acamprosate: A Case Report |
| title_short | Deterrent Action of Acamprosate: A Case Report |
| title_sort | deterrent action of acamprosate a case report |
| topic | adverse effects acamprosate urticaria |
| url | https://ahj.kmu.ac.ir/article_89570_4a68403a8c8f6b05ed165abfc652d130.pdf |
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