A Pathophysiological Intersection of Diabetes and Alzheimer’s Disease

A Pathophysiological Intersection of Diabetes and Alzheimer’s Disease

Diabetes is among the most prevalent diseases of the modern world and is strongly linked to an increased risk of numerous neurodegenerative disorders, although the exact pathophysiological mechanisms are not clear yet. Insulin resistance is a serious pathological condition, connecting type 2 diabete...

Full description

Bibliographic Details
Main Authors:	Maša Čater, Sabine M. Hölter
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Series:	International Journal of Molecular Sciences
Subjects:	diabetes insulin sensitivity Alzheimer’s disease brain cognition depression
Online Access:	https://www.mdpi.com/1422-0067/23/19/11562

Similar Items

Alzheimer’s Disease as Type 3 Diabetes: Common Pathophysiological Mechanisms between Alzheimer’s Disease and Type 2 Diabetes
by: Michalis Michailidis, et al.
Published: (2022-02-01)

Brain insulin resistance and Alzheimer’s disease: a systematic review
by: Luis Jesuino de Oliveira Andrade, et al.
Published: (2024-02-01)

Dementia in Diabetes: The Role of Hypoglycemia
by: Khaled Hameed Husain, et al.
Published: (2023-06-01)

Physiological Mechanisms Inherent to Diabetes Involved in the Development of Dementia: Alzheimer’s Disease
by: Himan Mohamed-Mohamed, et al.
Published: (2023-10-01)

Type 3 Diabetes and Its Role Implications in Alzheimer’s Disease
by: Thuy Trang Nguyen, et al.
Published: (2020-04-01)

The impact of depression on language function in individuals with Alzheimer’s disease: a pre/post-treatment design
by: Kyung Hee Yoon, et al.
Published: (2023-02-01)

Gut dysbiosis, insulin resistance and Alzheimer’s disease: review of a novel approach to neurodegeneration
by: Evelyn Lazar, et al.
Published: (2021-06-01)

Type 2 Diabetes Mellitus and Alzheimer’s Disease: Shared Molecular Mechanisms and Potential Common Therapeutic Targets
by: Rim Hamzé, et al.
Published: (2022-12-01)

NLRP3 Inflammasome Blocking as a Potential Treatment of Central Insulin Resistance in Early-Stage Alzheimer’s Disease
by: Yulia K. Komleva, et al.
Published: (2021-10-01)

Induction of Brain Insulin Resistance and Alzheimer’s Molecular Changes by Western Diet
by: Anna Mietelska-Porowska, et al.
Published: (2022-04-01)

Polyoxidovanadates a new therapeutic alternative for neurodegenerative and aging diseases
by: Sonia Irais Gonzalez-Cano, et al.
Published: (2024-01-01)

Comorbidity Genes of Alzheimer’s Disease and Type 2 Diabetes Associated with Memory and Cognitive Function
by: Seong Beom Cho
Published: (2024-02-01)

Mechanism involved in insulin resistance via accumulation of β-amyloid and neurofibrillary tangles: link between type 2 diabetes and Alzheimer’s disease
by: Rad SK, et al.
Published: (2018-11-01)

Serum Corticosterone and Insulin Resistance as Early Biomarkers in the hAPP23 Overexpressing Mouse Model of Alzheimer’s Disease
by: Jhana O. Hendrickx, et al.
Published: (2021-06-01)

Insulin and Insulin Resistance in Alzheimer’s Disease
by: Aleksandra Sędzikowska, et al.
Published: (2021-09-01)

Selenium and Selenoproteins at the Intersection of Type 2 Diabetes and Thyroid Pathophysiology
by: Francesca Gorini, et al.
Published: (2022-06-01)

The structure of the cognitive reserve in Alzheimer’s disease
by: A. Sidenkova
Published: (2021-04-01)

Renal Contributions in the Pathophysiology and Neuropathological Substrates Shared by Chronic Kidney Disease and Alzheimer’s Disease
by: Gabriela Dumitrita Stanciu, et al.
Published: (2020-08-01)

Metabolic mysteries of the mind: Investigating type 3 diabetes
by: Dar Mohd Altaf, et al.
Published: (2024-02-01)

The Deficits of Insulin Signal in Alzheimer’s Disease and the Mechanisms of Vanadium Compounds in Curing AD
by: Jinyi Yao, et al.
Published: (2023-07-01)

A review of the mechanisms of abnormal ceramide metabolism in type 2 diabetes mellitus, Alzheimer’s disease, and their co-morbidities
by: Yun Pan, et al.
Published: (2024-02-01)

The potential role of human islet amyloid polypeptide in type 2 diabetes mellitus and Alzheimer’s diseases
by: Mohammed Alrouji, et al.
Published: (2023-05-01)

Insulin resistance-related features are associated with cognitive decline: a cross-sectional study in adult patients with type 1 diabetes
by: Xiaolin Ji, et al.
Published: (2024-01-01)

Brain Glucose Metabolism in Health, Obesity, and Cognitive Decline—Does Insulin Have Anything to Do with It? A Narrative Review
by: Eleni Rebelos, et al.
Published: (2021-04-01)

Antidepressants in Alzheimer’s Disease: A Focus on the Role of Mirtazapine
by: Ana Salomé Correia, et al.
Published: (2021-09-01)

Hypoglycemic medicines in the treatment of Alzheimer’s disease: Pathophysiological links between AD and glucose metabolism
by: Yixuan Wang, et al.
Published: (2023-02-01)

Depression as a Risk Factor for Dementia and Alzheimer’s Disease
by: Vanesa Cantón-Habas, et al.
Published: (2020-10-01)

Effect of the turkish strategy game Mangala on cognitive functions in individuals with Alzheimer’s disease: A pilot study
by: Aziz DENGIZ, et al.
Published: (2023-06-01)

Insulin resistance and reduced brain glucose metabolism in the aetiology of Alzheimer’s disease
by: Amy L. Berger
Published: (2016-12-01)

Hypothesis on ontogenesis and pathophysiology of Alzheimer’s disease
by: Eduarda Dal Pisol Schwab, et al.
Published: (2022-11-01)

Cognitive dysfunctions in individuals with diabetes mellitus
by: Hye-Geum Kim
Published: (2019-09-01)

Brain-Derived Neurotrophic Factor Signaling in the Pathophysiology of Alzheimer’s Disease: Beneficial Effects of Flavonoids for Neuroprotection
by: Tadahiro Numakawa, et al.
Published: (2021-05-01)

Contributions of blood–brain barrier imaging to neurovascular unit pathophysiology of Alzheimer’s disease and related dementias
by: Yuto Uchida, et al.
Published: (2023-02-01)

Protective Effect of Intranasal Insulin Administration on Cognitive Functions and Neurogenesis in a Rat Model of Alzheimer\'s Disease
by: Z Eshrati, et al.
Published: (2023-03-01)

Disrupted topological organization of functional brain networks in Alzheimer’s disease patients with depressive symptoms
by: Zhongwei Guo, et al.
Published: (2022-12-01)

Adiponectin: The Potential Regulator and Therapeutic Target of Obesity and Alzheimer’s Disease
by: Jong Youl Kim, et al.
Published: (2020-09-01)

Testosterone profile in older men with Alzheimer's disease
by: Cristiana Roscito Arenella Dusi, et al.

Dietary Patterns and Alzheimer’s Disease: An Updated Review Linking Nutrition to Neuroscience
by: Ines Ellouze, et al.
Published: (2023-07-01)

Rebuilding insight into the pathophysiology of Alzheimer's disease through new blood-brain barrier models
by: Kinya Matsuo, et al.
Published: (2024-01-01)

Clinical Features of Patients with Alzheimer’s Disease and a History of Traumatic Brain Injury
by: Suzan van Amerongen, et al.
Published: (2022-09-01)