CaSiO<sub>3</sub>-HAp Metal-Reinforced Biocomposite Ceramics for Bone Tissue Engineering
Reconstructive and regenerative bone surgery is based on the use of high-tech biocompatible implants needed to restore the functions of the musculoskeletal system of patients. Ti6Al4V is one of the most widely used titanium alloys for a variety of applications where low density and excellent corrosi...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Journal of Functional Biomaterials |
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| Online Access: | https://www.mdpi.com/2079-4983/14/5/259 |
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| author | Evgeniy K. Papynov Oleg O. Shichalin Anton A. Belov Igor Yu Buravlev Vitaly Yu Mayorov Alexander N. Fedorets Anastasiya A. Buravleva Alexey O. Lembikov Danila V. Gritsuk Olesya V. Kapustina Zlata E. Kornakova |
| author_facet | Evgeniy K. Papynov Oleg O. Shichalin Anton A. Belov Igor Yu Buravlev Vitaly Yu Mayorov Alexander N. Fedorets Anastasiya A. Buravleva Alexey O. Lembikov Danila V. Gritsuk Olesya V. Kapustina Zlata E. Kornakova |
| author_sort | Evgeniy K. Papynov |
| collection | DOAJ |
| description | Reconstructive and regenerative bone surgery is based on the use of high-tech biocompatible implants needed to restore the functions of the musculoskeletal system of patients. Ti6Al4V is one of the most widely used titanium alloys for a variety of applications where low density and excellent corrosion resistance are required, including biomechanical applications (implants and prostheses). Calcium silicate or wollastonite (CaSiO<sub>3</sub>) and calcium hydroxyapatite (HAp) is a bioceramic material used in biomedicine due to its bioactive properties, which can potentially be used for bone repair. In this regard, the research investigates the possibility of using spark plasma sintering technology to obtain new CaSiO<sub>3</sub>-HAp biocomposite ceramics reinforced with a Ti6Al4V titanium alloy matrix obtained by additive manufacturing. The phase and elemental compositions, structure, and morphology of the initial CaSiO<sub>3</sub>-HAp powder and its ceramic metal biocomposite were studied by X-ray fluorescence, scanning electron microscopy, energy-dispersive X-ray spectroscopy, and Brunauer–Emmett–Teller analysis methods. The spark plasma sintering technology was shown to be efficient for the consolidation of CaSiO<sub>3</sub>-HAp powder in volume with a Ti6Al4V reinforcing matrix to obtain a ceramic metal biocomposite of an integral form. Vickers microhardness values were determined for the alloy and bioceramics (~500 and 560 HV, respectively), as well as for their interface area (~640 HV). An assessment of the critical stress intensity factor <i>K</i><sub>I<i>c</i></sub> (crack resistance) was performed. The research result is new and represents a prospect for the creation of high-tech implant products for regenerative bone surgery. |
| first_indexed | 2024-03-11T03:36:30Z |
| format | Article |
| id | doaj.art-76d80f9c3abd4b6a82f09d589bc61884 |
| institution | Directory Open Access Journal |
| issn | 2079-4983 |
| language | English |
| last_indexed | 2024-03-11T03:36:30Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Functional Biomaterials |
| spelling | doaj.art-76d80f9c3abd4b6a82f09d589bc618842023-11-18T01:56:50ZengMDPI AGJournal of Functional Biomaterials2079-49832023-05-0114525910.3390/jfb14050259CaSiO<sub>3</sub>-HAp Metal-Reinforced Biocomposite Ceramics for Bone Tissue EngineeringEvgeniy K. Papynov0Oleg O. Shichalin1Anton A. Belov2Igor Yu Buravlev3Vitaly Yu Mayorov4Alexander N. Fedorets5Anastasiya A. Buravleva6Alexey O. Lembikov7Danila V. Gritsuk8Olesya V. Kapustina9Zlata E. Kornakova10Far Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, RussiaFar Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, RussiaFar Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, RussiaFar Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, RussiaFar Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, RussiaFar Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, RussiaFar Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, RussiaFar Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, RussiaFar Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, RussiaFar Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, RussiaFar Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, RussiaReconstructive and regenerative bone surgery is based on the use of high-tech biocompatible implants needed to restore the functions of the musculoskeletal system of patients. Ti6Al4V is one of the most widely used titanium alloys for a variety of applications where low density and excellent corrosion resistance are required, including biomechanical applications (implants and prostheses). Calcium silicate or wollastonite (CaSiO<sub>3</sub>) and calcium hydroxyapatite (HAp) is a bioceramic material used in biomedicine due to its bioactive properties, which can potentially be used for bone repair. In this regard, the research investigates the possibility of using spark plasma sintering technology to obtain new CaSiO<sub>3</sub>-HAp biocomposite ceramics reinforced with a Ti6Al4V titanium alloy matrix obtained by additive manufacturing. The phase and elemental compositions, structure, and morphology of the initial CaSiO<sub>3</sub>-HAp powder and its ceramic metal biocomposite were studied by X-ray fluorescence, scanning electron microscopy, energy-dispersive X-ray spectroscopy, and Brunauer–Emmett–Teller analysis methods. The spark plasma sintering technology was shown to be efficient for the consolidation of CaSiO<sub>3</sub>-HAp powder in volume with a Ti6Al4V reinforcing matrix to obtain a ceramic metal biocomposite of an integral form. Vickers microhardness values were determined for the alloy and bioceramics (~500 and 560 HV, respectively), as well as for their interface area (~640 HV). An assessment of the critical stress intensity factor <i>K</i><sub>I<i>c</i></sub> (crack resistance) was performed. The research result is new and represents a prospect for the creation of high-tech implant products for regenerative bone surgery.https://www.mdpi.com/2079-4983/14/5/259selective laser meltingspark plasma sinteringwollastonite/hydroxyapatitebone tissuescaffolds |
| spellingShingle | Evgeniy K. Papynov Oleg O. Shichalin Anton A. Belov Igor Yu Buravlev Vitaly Yu Mayorov Alexander N. Fedorets Anastasiya A. Buravleva Alexey O. Lembikov Danila V. Gritsuk Olesya V. Kapustina Zlata E. Kornakova CaSiO<sub>3</sub>-HAp Metal-Reinforced Biocomposite Ceramics for Bone Tissue Engineering Journal of Functional Biomaterials selective laser melting spark plasma sintering wollastonite/hydroxyapatite bone tissue scaffolds |
| title | CaSiO<sub>3</sub>-HAp Metal-Reinforced Biocomposite Ceramics for Bone Tissue Engineering |
| title_full | CaSiO<sub>3</sub>-HAp Metal-Reinforced Biocomposite Ceramics for Bone Tissue Engineering |
| title_fullStr | CaSiO<sub>3</sub>-HAp Metal-Reinforced Biocomposite Ceramics for Bone Tissue Engineering |
| title_full_unstemmed | CaSiO<sub>3</sub>-HAp Metal-Reinforced Biocomposite Ceramics for Bone Tissue Engineering |
| title_short | CaSiO<sub>3</sub>-HAp Metal-Reinforced Biocomposite Ceramics for Bone Tissue Engineering |
| title_sort | casio sub 3 sub hap metal reinforced biocomposite ceramics for bone tissue engineering |
| topic | selective laser melting spark plasma sintering wollastonite/hydroxyapatite bone tissue scaffolds |
| url | https://www.mdpi.com/2079-4983/14/5/259 |
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