Ion-Pair Compounds of Strychnine for Enhancing Skin Permeability: Influencing the Transdermal Processes In Vitro Based on Molecular Simulation

Ion-Pair Compounds of Strychnine for Enhancing Skin Permeability: Influencing the Transdermal Processes In Vitro Based on Molecular Simulation

This research aimed to explore how Strychnine (Str) ion-pair compounds affect the in vitro transdermal process. In order to prevent the influence of different functional groups on skin permeation, seven homologous fatty acids were selected to form ion-pair compounds with Str. The in vitro permeation...

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Bibliographic Details
Main Authors: Lili He, Di Xiong, Lan Ma, Yan Liang, Teng Zhang, Zhiming Wu, Huaibo Tang, Xuewen Wu
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceuticals
Subjects:
strychnine
ion-pair
transdermal
molecular simulation
Online Access:https://www.mdpi.com/1424-8247/15/1/34

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