Physiological synaptic activity and recognition memory require astroglial glutamine
The authors present a fluorescent probe that tracks glutamine in live cells. They demonstrate the capabilities of the probe by providing direct visual evidence of an activity-dependent glutamine supply from astroglial networks to presynaptic structures under physiological conditions.
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-28331-7 |
| _version_ | 1819274847165874176 |
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| author | Giselle Cheung Danijela Bataveljic Josien Visser Naresh Kumar Julien Moulard Glenn Dallérac Daria Mozheiko Astrid Rollenhagen Pascal Ezan Cédric Mongin Oana Chever Alexis-Pierre Bemelmans Joachim Lübke Isabelle Leray Nathalie Rouach |
| author_facet | Giselle Cheung Danijela Bataveljic Josien Visser Naresh Kumar Julien Moulard Glenn Dallérac Daria Mozheiko Astrid Rollenhagen Pascal Ezan Cédric Mongin Oana Chever Alexis-Pierre Bemelmans Joachim Lübke Isabelle Leray Nathalie Rouach |
| author_sort | Giselle Cheung |
| collection | DOAJ |
| description | The authors present a fluorescent probe that tracks glutamine in live cells. They demonstrate the capabilities of the probe by providing direct visual evidence of an activity-dependent glutamine supply from astroglial networks to presynaptic structures under physiological conditions. |
| first_indexed | 2024-12-23T23:14:56Z |
| format | Article |
| id | doaj.art-76d9e045d8fc48bdbc6eb629f33bd9bc |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-23T23:14:56Z |
| publishDate | 2022-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-76d9e045d8fc48bdbc6eb629f33bd9bc2022-12-21T17:26:31ZengNature PortfolioNature Communications2041-17232022-02-0113111710.1038/s41467-022-28331-7Physiological synaptic activity and recognition memory require astroglial glutamineGiselle Cheung0Danijela Bataveljic1Josien Visser2Naresh Kumar3Julien Moulard4Glenn Dallérac5Daria Mozheiko6Astrid Rollenhagen7Pascal Ezan8Cédric Mongin9Oana Chever10Alexis-Pierre Bemelmans11Joachim Lübke12Isabelle Leray13Nathalie Rouach14Neuroglial Interactions in Cerebral Physiology and Pathologies, Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, Labex Memolife, Université PSLNeuroglial Interactions in Cerebral Physiology and Pathologies, Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, Labex Memolife, Université PSLNeuroglial Interactions in Cerebral Physiology and Pathologies, Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, Labex Memolife, Université PSLUniversité Paris Saclay, ENS Paris-Saclay, CNRS, PPSMNeuroglial Interactions in Cerebral Physiology and Pathologies, Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, Labex Memolife, Université PSLNeuroglial Interactions in Cerebral Physiology and Pathologies, Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, Labex Memolife, Université PSLNeuroglial Interactions in Cerebral Physiology and Pathologies, Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, Labex Memolife, Université PSLInstitute for Neuroscience and Medicine INM-10, Research Center JülichNeuroglial Interactions in Cerebral Physiology and Pathologies, Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, Labex Memolife, Université PSLUniversité Paris Saclay, ENS Paris-Saclay, CNRS, PPSMNeuroglial Interactions in Cerebral Physiology and Pathologies, Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, Labex Memolife, Université PSLCommissariat à l’Energie Atomique et aux Energies Alternatives, Département de la Recherche Fondamentale, Institut de biologie François Jacob, Molecular Imaging Research Center and CNRS UMR9199, Université Paris-Sud, Neurodegenerative Diseases LaboratoryInstitute for Neuroscience and Medicine INM-10, Research Center JülichUniversité Paris Saclay, ENS Paris-Saclay, CNRS, PPSMNeuroglial Interactions in Cerebral Physiology and Pathologies, Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, Labex Memolife, Université PSLThe authors present a fluorescent probe that tracks glutamine in live cells. They demonstrate the capabilities of the probe by providing direct visual evidence of an activity-dependent glutamine supply from astroglial networks to presynaptic structures under physiological conditions.https://doi.org/10.1038/s41467-022-28331-7 |
| spellingShingle | Giselle Cheung Danijela Bataveljic Josien Visser Naresh Kumar Julien Moulard Glenn Dallérac Daria Mozheiko Astrid Rollenhagen Pascal Ezan Cédric Mongin Oana Chever Alexis-Pierre Bemelmans Joachim Lübke Isabelle Leray Nathalie Rouach Physiological synaptic activity and recognition memory require astroglial glutamine Nature Communications |
| title | Physiological synaptic activity and recognition memory require astroglial glutamine |
| title_full | Physiological synaptic activity and recognition memory require astroglial glutamine |
| title_fullStr | Physiological synaptic activity and recognition memory require astroglial glutamine |
| title_full_unstemmed | Physiological synaptic activity and recognition memory require astroglial glutamine |
| title_short | Physiological synaptic activity and recognition memory require astroglial glutamine |
| title_sort | physiological synaptic activity and recognition memory require astroglial glutamine |
| url | https://doi.org/10.1038/s41467-022-28331-7 |
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