Microtubules provide directional information for core PCP function

Microtubules provide directional information for core PCP function

Planar cell polarity (PCP) signaling controls the polarization of cells within the plane of an epithelium. Two molecular modules composed of Fat(Ft)/Dachsous(Ds)/Four-jointed(Fj) and a ‘PCP-core’ including Frizzled(Fz) and Dishevelled(Dsh) contribute to polarization of individual cells. How polarity...

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Bibliographic Details
Main Authors: Maja Matis, David A Russler-Germain, Qie Hu, Claire J Tomlin, Jeffrey D Axelrod
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-08-01
Series:eLife
Subjects:
planar cell polarity
fat cadherin
microtubules
Online Access:https://elifesciences.org/articles/02893

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