Thai Patients’ Drug Safety Knowledge and Perceptions Relating to Different Forms of Written Medicine Information: A Comparative Study

Kamonphat Wongtaweepkij,1 Janet Krska,2 Supawinee Pongpunna,3 Juraporn Pongwecharak,4 Narumol Jarernsiripornkul1 1Division of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand; 2Medway School of Pharmacy, The Universities of Greenwich and Kent, Kent, UK...

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Main Authors: Wongtaweepkij K, Krska J, Pongpunna S, Pongwecharak J, Jarernsiripornkul N
Format: Article
Language:English
Published: Dove Medical Press 2022-04-01
Series:Patient Preference and Adherence
Subjects:
Online Access:https://www.dovepress.com/thai-patients-drug-safety-knowledge-and-perceptions-relating-to-differ-peer-reviewed-fulltext-article-PPA
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author Wongtaweepkij K
Krska J
Pongpunna S
Pongwecharak J
Jarernsiripornkul N
author_facet Wongtaweepkij K
Krska J
Pongpunna S
Pongwecharak J
Jarernsiripornkul N
author_sort Wongtaweepkij K
collection DOAJ
description Kamonphat Wongtaweepkij,1 Janet Krska,2 Supawinee Pongpunna,3 Juraporn Pongwecharak,4 Narumol Jarernsiripornkul1 1Division of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand; 2Medway School of Pharmacy, The Universities of Greenwich and Kent, Kent, UK; 3Pharmacy Department, Queen Sirikit Heart Centre of the Northeast, Khon Kaen, Thailand; 4Division of Pharmaceutical Care, Faculty of Pharmacy, Rangsit Center, Thammasat University, Pathumthani, ThailandCorrespondence: Narumol Jarernsiripornkul, Division of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand, Email narumol@kku.ac.thPurpose: The aim of the study was to evaluate the medication safety knowledge, quality of the written medicine information (WMI), and perceptions of taking the medicines in patients receiving package inserts (PIs) in comparison with patient information leaflets (PILs).Methods: A cross-sectional, comparative study was conducted from December 2020 to May 2021 at two university hospitals in Thailand. Outpatients who visited the pharmacy departments and were prescribed one of the three medicines: atorvastatin, celecoxib, or metformin were randomly selected by a permuted block randomization. The medication safety knowledge was measured using a set of validated and closed questions. The quality of the WMI was measured by the Consumer Information Rating Form (CIRF). Satisfaction with information and perceptions of the benefits and risks of medications were rated by the participants using a visual analog scale (0 to 10).Results: Of the 1150 invited patients, 750 completed the questionnaires (65.2%). A higher proportion of respondents with high level of medication safety knowledge was found in those reading the PILs than the PIs (44.5% and 20.8%, respectively). The type of leaflet received was a significant predictor of the high knowledge level (p < 0.001). The mean CIRF scores were significantly higher among those reading the PILs than the PIs (p < 0.001). Patients reading the PILs were also more satisfied with the information and had more positive perceptions of the benefits from taking medicines and intention to adhere than those reading the PIs. Patients’ perceptions of risks after reading both leaflets were moderate (median score = 5.0), with the PIL group having slightly more concern about risks than the PI group.Conclusion: The PILs showed superior effectiveness to the PIs in enhancing knowledge about medication safety, providing greater satisfaction with the information, and positive perceptions of benefit and intention to comply with the medications. PILs should be provided more frequently to patients receiving medicines than PIs.Keywords: patient information leaflets, package inserts, medication safety knowledge, consumer testing, perceptions of benefits and risks
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spelling doaj.art-76dec7f116214b359928468d9bb2467b2022-12-22T02:08:07ZengDove Medical PressPatient Preference and Adherence1177-889X2022-04-01Volume 161141115274947Thai Patients&rsquo; Drug Safety Knowledge and Perceptions Relating to Different Forms of Written Medicine Information: A Comparative StudyWongtaweepkij KKrska JPongpunna SPongwecharak JJarernsiripornkul NKamonphat Wongtaweepkij,1 Janet Krska,2 Supawinee Pongpunna,3 Juraporn Pongwecharak,4 Narumol Jarernsiripornkul1 1Division of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand; 2Medway School of Pharmacy, The Universities of Greenwich and Kent, Kent, UK; 3Pharmacy Department, Queen Sirikit Heart Centre of the Northeast, Khon Kaen, Thailand; 4Division of Pharmaceutical Care, Faculty of Pharmacy, Rangsit Center, Thammasat University, Pathumthani, ThailandCorrespondence: Narumol Jarernsiripornkul, Division of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand, Email narumol@kku.ac.thPurpose: The aim of the study was to evaluate the medication safety knowledge, quality of the written medicine information (WMI), and perceptions of taking the medicines in patients receiving package inserts (PIs) in comparison with patient information leaflets (PILs).Methods: A cross-sectional, comparative study was conducted from December 2020 to May 2021 at two university hospitals in Thailand. Outpatients who visited the pharmacy departments and were prescribed one of the three medicines: atorvastatin, celecoxib, or metformin were randomly selected by a permuted block randomization. The medication safety knowledge was measured using a set of validated and closed questions. The quality of the WMI was measured by the Consumer Information Rating Form (CIRF). Satisfaction with information and perceptions of the benefits and risks of medications were rated by the participants using a visual analog scale (0 to 10).Results: Of the 1150 invited patients, 750 completed the questionnaires (65.2%). A higher proportion of respondents with high level of medication safety knowledge was found in those reading the PILs than the PIs (44.5% and 20.8%, respectively). The type of leaflet received was a significant predictor of the high knowledge level (p < 0.001). The mean CIRF scores were significantly higher among those reading the PILs than the PIs (p < 0.001). Patients reading the PILs were also more satisfied with the information and had more positive perceptions of the benefits from taking medicines and intention to adhere than those reading the PIs. Patients’ perceptions of risks after reading both leaflets were moderate (median score = 5.0), with the PIL group having slightly more concern about risks than the PI group.Conclusion: The PILs showed superior effectiveness to the PIs in enhancing knowledge about medication safety, providing greater satisfaction with the information, and positive perceptions of benefit and intention to comply with the medications. PILs should be provided more frequently to patients receiving medicines than PIs.Keywords: patient information leaflets, package inserts, medication safety knowledge, consumer testing, perceptions of benefits and riskshttps://www.dovepress.com/thai-patients-drug-safety-knowledge-and-perceptions-relating-to-differ-peer-reviewed-fulltext-article-PPApatient information leafletspackage insertsmedication safety knowledgeconsumer testingperceptions of benefits and risks
spellingShingle Wongtaweepkij K
Krska J
Pongpunna S
Pongwecharak J
Jarernsiripornkul N
Thai Patients&rsquo; Drug Safety Knowledge and Perceptions Relating to Different Forms of Written Medicine Information: A Comparative Study
Patient Preference and Adherence
patient information leaflets
package inserts
medication safety knowledge
consumer testing
perceptions of benefits and risks
title Thai Patients&rsquo; Drug Safety Knowledge and Perceptions Relating to Different Forms of Written Medicine Information: A Comparative Study
title_full Thai Patients&rsquo; Drug Safety Knowledge and Perceptions Relating to Different Forms of Written Medicine Information: A Comparative Study
title_fullStr Thai Patients&rsquo; Drug Safety Knowledge and Perceptions Relating to Different Forms of Written Medicine Information: A Comparative Study
title_full_unstemmed Thai Patients&rsquo; Drug Safety Knowledge and Perceptions Relating to Different Forms of Written Medicine Information: A Comparative Study
title_short Thai Patients&rsquo; Drug Safety Knowledge and Perceptions Relating to Different Forms of Written Medicine Information: A Comparative Study
title_sort thai patients rsquo drug safety knowledge and perceptions relating to different forms of written medicine information a comparative study
topic patient information leaflets
package inserts
medication safety knowledge
consumer testing
perceptions of benefits and risks
url https://www.dovepress.com/thai-patients-drug-safety-knowledge-and-perceptions-relating-to-differ-peer-reviewed-fulltext-article-PPA
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