The combined effects of microglia activation and brain glucose hypometabolism in early-onset Alzheimer’s disease
Abstract Background Early-onset Alzheimer’s disease (EOAD) is characterized by young age of onset (< 65 years), severe neurodegeneration, and rapid disease progression, thus differing significantly from typical late-onset Alzheimer’s disease. Growing evidence suggests a primary role of neuroinfla...
Main Authors: | Giacomo Tondo, Leonardo Iaccarino, Silvia Paola Caminiti, Luca Presotto, Roberto Santangelo, Sandro Iannaccone, Giuseppe Magnani, Daniela Perani |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Alzheimer’s Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13195-020-00619-0 |
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