Early Detection of Secondary Bladder Urothelial Carcinoma and Disseminated Bone Metastases with Normal Prostate-Specific Antigen Level after Pelvic Salvage Radiotherapy in Prostate Cancer

This report describes the case of a 65-year-old man who presented with gross hematuria and a history of pelvic salvage radiotherapy for prostate cancer. Cystoscopy and transurethral resection of the bladder revealed urothelial carcinoma. Subsequently, disseminated bone metastases were detected with...

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Main Authors: Teak Jun Shin, Misun Choe, Byung Hoon Kim, Sang Jun Byun
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/13/6/1249
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author Teak Jun Shin
Misun Choe
Byung Hoon Kim
Sang Jun Byun
author_facet Teak Jun Shin
Misun Choe
Byung Hoon Kim
Sang Jun Byun
author_sort Teak Jun Shin
collection DOAJ
description This report describes the case of a 65-year-old man who presented with gross hematuria and a history of pelvic salvage radiotherapy for prostate cancer. Cystoscopy and transurethral resection of the bladder revealed urothelial carcinoma. Subsequently, disseminated bone metastases were detected with normal prostate-specific antigen (PSA) levels, and palliative radiotherapy and systemic chemotherapy were administered. Because gross hematuria can appear in both acute/chronic cystitis and bladder cancer in patients who have undergone pelvic radiotherapy for prostate cancer, close follow-up along with a detailed evaluation is needed. In addition, because prostate cancer disease progression with normal PSA levels may be associated with specific pathological findings, a detailed evaluation of symptoms and a careful review of pathologic reports are important.
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spelling doaj.art-76e82d4660d24acc8f9f11498d5f989c2023-11-18T11:16:41ZengMDPI AGLife2075-17292023-05-01136124910.3390/life13061249Early Detection of Secondary Bladder Urothelial Carcinoma and Disseminated Bone Metastases with Normal Prostate-Specific Antigen Level after Pelvic Salvage Radiotherapy in Prostate CancerTeak Jun Shin0Misun Choe1Byung Hoon Kim2Sang Jun Byun3Department of Urology, Keimyung University School of Medicine, Daegu 42601, Republic of KoreaDepartment of Pathology, Keimyung University School of Medicine, Daegu 42601, Republic of KoreaDepartment of Urology, Keimyung University School of Medicine, Daegu 42601, Republic of KoreaDepartment of Radiation Oncology, Keimyung University School of Medicine, Daegu 42601, Republic of KoreaThis report describes the case of a 65-year-old man who presented with gross hematuria and a history of pelvic salvage radiotherapy for prostate cancer. Cystoscopy and transurethral resection of the bladder revealed urothelial carcinoma. Subsequently, disseminated bone metastases were detected with normal prostate-specific antigen (PSA) levels, and palliative radiotherapy and systemic chemotherapy were administered. Because gross hematuria can appear in both acute/chronic cystitis and bladder cancer in patients who have undergone pelvic radiotherapy for prostate cancer, close follow-up along with a detailed evaluation is needed. In addition, because prostate cancer disease progression with normal PSA levels may be associated with specific pathological findings, a detailed evaluation of symptoms and a careful review of pathologic reports are important.https://www.mdpi.com/2075-1729/13/6/1249prostate cancerpelvic radiotherapysecondary bladder cancerbone metastasesnormal prostate-specific antigen
spellingShingle Teak Jun Shin
Misun Choe
Byung Hoon Kim
Sang Jun Byun
Early Detection of Secondary Bladder Urothelial Carcinoma and Disseminated Bone Metastases with Normal Prostate-Specific Antigen Level after Pelvic Salvage Radiotherapy in Prostate Cancer
Life
prostate cancer
pelvic radiotherapy
secondary bladder cancer
bone metastases
normal prostate-specific antigen
title Early Detection of Secondary Bladder Urothelial Carcinoma and Disseminated Bone Metastases with Normal Prostate-Specific Antigen Level after Pelvic Salvage Radiotherapy in Prostate Cancer
title_full Early Detection of Secondary Bladder Urothelial Carcinoma and Disseminated Bone Metastases with Normal Prostate-Specific Antigen Level after Pelvic Salvage Radiotherapy in Prostate Cancer
title_fullStr Early Detection of Secondary Bladder Urothelial Carcinoma and Disseminated Bone Metastases with Normal Prostate-Specific Antigen Level after Pelvic Salvage Radiotherapy in Prostate Cancer
title_full_unstemmed Early Detection of Secondary Bladder Urothelial Carcinoma and Disseminated Bone Metastases with Normal Prostate-Specific Antigen Level after Pelvic Salvage Radiotherapy in Prostate Cancer
title_short Early Detection of Secondary Bladder Urothelial Carcinoma and Disseminated Bone Metastases with Normal Prostate-Specific Antigen Level after Pelvic Salvage Radiotherapy in Prostate Cancer
title_sort early detection of secondary bladder urothelial carcinoma and disseminated bone metastases with normal prostate specific antigen level after pelvic salvage radiotherapy in prostate cancer
topic prostate cancer
pelvic radiotherapy
secondary bladder cancer
bone metastases
normal prostate-specific antigen
url https://www.mdpi.com/2075-1729/13/6/1249
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