A logical network-based drug-screening platform for Alzheimer’s disease representing pathological features of human brain organoids
Developing effective drugs for Alzheimer’s disease (AD), the most common cause of dementia, has been difficult because of complicated pathogenesis. Here, the authors report an efficient network-based drug-screening platform developed by integrating mathematical modeling and the pathological features...
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Bibliographic Details
| Main Authors: |
Jong-Chan Park,
So-Yeong Jang,
Dongjoon Lee,
Jeongha Lee,
Uiryong Kang,
Hongjun Chang,
Haeng Jun Kim,
Sun-Ho Han,
Jinsoo Seo,
Murim Choi,
Dong Young Lee,
Min Soo Byun,
Dahyun Yi,
Kwang-Hyun Cho,
Inhee Mook-Jung |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2021-01-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-20440-5
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