Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture

RNA interactome capture allows the detailed investigation of RNA-bound proteomes. Here the authors describe enhanced RNA-interactome capture using LNA-modified probes for increased sensitivity and specificity.

Dettagli Bibliografici
Autori principali: Joel I. Perez-Perri, Birgit Rogell, Thomas Schwarzl, Frank Stein, Yang Zhou, Mandy Rettel, Annika Brosig, Matthias W. Hentze
Natura: Articolo
Lingua:English
Pubblicazione: Nature Portfolio 2018-10-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-018-06557-8