Impact of Progerin Expression on Adipogenesis in Hutchinson—Gilford Progeria Skin-Derived Precursor Cells

Impact of Progerin Expression on Adipogenesis in Hutchinson—Gilford Progeria Skin-Derived Precursor Cells

Hutchinson–Gilford progeria syndrome (HGPS) is a segmental premature aging disease caused by a mutation in <i>LMNA</i>. The mutation generates a truncated and farnesylated form of prelamin A, called progerin. Affected individuals develop several features of normal aging, including lipody...

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Bibliographic Details
Main Authors: Farah Najdi, Peter Krüger, Karima Djabali
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
progerin
senescence
adipocyte
skin-derived precursor cells
adipogenesis
Online Access:https://www.mdpi.com/2073-4409/10/7/1598

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