Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial
Objective: The diagnosis and treatment of breast cancer is associated with significant distress that has huge impact on survivors’ quality of life. The objective of this study is to assess the effectiveness of an integrated intervention “Moving on After Breast Cancer (ABC) Plus culturally adapted Co...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-06-01
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| Series: | SAGE Open Medicine |
| Online Access: | https://doi.org/10.1177/20503121231177549 |
| _version_ | 1797792299535564800 |
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| author | Nusrat Husain Tayyeba Kiran Imran B Chaudhry Sarwat Sultan Saima Dawood Farah Lunat Asad Nizami Lisa Shanahan Afshan Qureshi Zaib Un Nisa Mina Husain Suleman Shakoor Mohsin H Alvi Zainab Zadeh Rakhshi Memon Nasim Chaudhry |
| author_facet | Nusrat Husain Tayyeba Kiran Imran B Chaudhry Sarwat Sultan Saima Dawood Farah Lunat Asad Nizami Lisa Shanahan Afshan Qureshi Zaib Un Nisa Mina Husain Suleman Shakoor Mohsin H Alvi Zainab Zadeh Rakhshi Memon Nasim Chaudhry |
| author_sort | Nusrat Husain |
| collection | DOAJ |
| description | Objective: The diagnosis and treatment of breast cancer is associated with significant distress that has huge impact on survivors’ quality of life. The objective of this study is to assess the effectiveness of an integrated intervention “Moving on After Breast Cancer (ABC) Plus culturally adapted Cognitive Behavior Therapy” (Moving on ABC Plus). Method: This is a randomized controlled trial that aims to recruit 354 breast cancer survivors from the inpatient and outpatient oncology departments in public and private hospitals in Karachi, Hyderabad, Lahore, Multan, and Rawalpindi in Pakistan. Patients scoring 10 or above on either the Patient Health Questionnaire—9 and/or the Generalized Anxiety Disorder scale (GAD-7) will be recruited. Baseline assessments will include Functional Assessment of Cancer Therapy—Breast; EuroQol-5D; Multidimensional Scale for Perceived Social Support; Intrusive Thoughts Scale; and Rosenberg Self-Esteem Scale. Participants randomized into intervention arm, Moving on ABC Plus, will receive 12 individual therapy sessions over 4 months. Follow-up will be completed at 4- and 6-month post-randomization, using all baseline instruments along with the Client Satisfaction Questionnaire (CSQ-8). We will also explore the participants’, their family members’, and the therapists’ experiences of the trial and intervention. Results: We will be assessing the effectiveness of intervention in reducing depression and anxiety in breast cancer survivors as a primary outcome of the trial. The secondary outcomes will include effectiveness of intervention in terms of reduction in intrusive thoughts and improvement in health-related quality of life, self-esteem, and perceived social support. Conclusion: The results of the study will inform the design of a future larger randomized control trial with long-term follow-up. |
| first_indexed | 2024-03-13T02:32:15Z |
| format | Article |
| id | doaj.art-76ece1930cac47b192cb4d4d2f036390 |
| institution | Directory Open Access Journal |
| issn | 2050-3121 |
| language | English |
| last_indexed | 2024-03-13T02:32:15Z |
| publishDate | 2023-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | SAGE Open Medicine |
| spelling | doaj.art-76ece1930cac47b192cb4d4d2f0363902023-06-29T14:03:55ZengSAGE PublishingSAGE Open Medicine2050-31212023-06-011110.1177/20503121231177549Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trialNusrat Husain0Tayyeba Kiran1Imran B Chaudhry2Sarwat Sultan3Saima Dawood4Farah Lunat5Asad Nizami6Lisa Shanahan7Afshan Qureshi8Zaib Un Nisa9Mina Husain10Suleman Shakoor11Mohsin H Alvi12Zainab Zadeh13Rakhshi Memon14Nasim Chaudhry15Manchester Global foundation, Manchester, UKPakistan Institute of Living and Learning, Karachi, PakistanZiauddin University and Hospital, Karachi, PakistanDepartment of Psychology, Bahauddin Zakaria University, Multan, PakistanCenter for Clinical Psychology, University of Punjab, Lahore, PakistanLancashire and South Cumbria NHS Foundation Trust, Preston, UKInstitute of Psychiatry, Benazir Bhutto Hospital, Rawalpindi, PakistanManchester Global foundation, Manchester, UKPakistan Institute of Living and Learning, Karachi, PakistanPakistan Institute of Living and Learning, Karachi, PakistanSouth London and Maudsley NHS Foundation Trust, London, UKPakistan Institute of Living and Learning, Karachi, PakistanPakistan Institute of Living and Learning, Karachi, PakistanPakistan Institute of Living and Learning, Karachi, PakistanDepartment of Science and Technology Studies, University College London, London, UKPakistan Institute of Living and Learning, Karachi, PakistanObjective: The diagnosis and treatment of breast cancer is associated with significant distress that has huge impact on survivors’ quality of life. The objective of this study is to assess the effectiveness of an integrated intervention “Moving on After Breast Cancer (ABC) Plus culturally adapted Cognitive Behavior Therapy” (Moving on ABC Plus). Method: This is a randomized controlled trial that aims to recruit 354 breast cancer survivors from the inpatient and outpatient oncology departments in public and private hospitals in Karachi, Hyderabad, Lahore, Multan, and Rawalpindi in Pakistan. Patients scoring 10 or above on either the Patient Health Questionnaire—9 and/or the Generalized Anxiety Disorder scale (GAD-7) will be recruited. Baseline assessments will include Functional Assessment of Cancer Therapy—Breast; EuroQol-5D; Multidimensional Scale for Perceived Social Support; Intrusive Thoughts Scale; and Rosenberg Self-Esteem Scale. Participants randomized into intervention arm, Moving on ABC Plus, will receive 12 individual therapy sessions over 4 months. Follow-up will be completed at 4- and 6-month post-randomization, using all baseline instruments along with the Client Satisfaction Questionnaire (CSQ-8). We will also explore the participants’, their family members’, and the therapists’ experiences of the trial and intervention. Results: We will be assessing the effectiveness of intervention in reducing depression and anxiety in breast cancer survivors as a primary outcome of the trial. The secondary outcomes will include effectiveness of intervention in terms of reduction in intrusive thoughts and improvement in health-related quality of life, self-esteem, and perceived social support. Conclusion: The results of the study will inform the design of a future larger randomized control trial with long-term follow-up.https://doi.org/10.1177/20503121231177549 |
| spellingShingle | Nusrat Husain Tayyeba Kiran Imran B Chaudhry Sarwat Sultan Saima Dawood Farah Lunat Asad Nizami Lisa Shanahan Afshan Qureshi Zaib Un Nisa Mina Husain Suleman Shakoor Mohsin H Alvi Zainab Zadeh Rakhshi Memon Nasim Chaudhry Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial SAGE Open Medicine |
| title | Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial |
| title_full | Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial |
| title_fullStr | Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial |
| title_full_unstemmed | Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial |
| title_short | Integrated Moving on After Breast Cancer and Culturally Adapted Cognitive Behavior Therapy intervention for depression and anxiety among Pakistani women with breast cancer: Protocol of a randomized controlled trial |
| title_sort | integrated moving on after breast cancer and culturally adapted cognitive behavior therapy intervention for depression and anxiety among pakistani women with breast cancer protocol of a randomized controlled trial |
| url | https://doi.org/10.1177/20503121231177549 |
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