Analysis of Three-Dimensional Characteristics in Tumor Morphology
Precise assessment of therapeutic response in radiotherapy has been an important issue in the field of radiation oncology. This study proposed a methodology to evaluate therapeutic response based on tumor geometries. Three-dimensional (3D) tumor shapes were obtained from follow-up CT scans taken onc...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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The Japan Society of Mechanical Engineers
2009-05-01
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| Series: | Journal of Biomechanical Science and Engineering |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jbse/4/2/4_2_221/_pdf/-char/en |
| _version_ | 1811292413607542784 |
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| author | Seishin TAKAO Shigeru TADANO Hiroshi TAGUCHI Hiroki SHIRATO |
| author_facet | Seishin TAKAO Shigeru TADANO Hiroshi TAGUCHI Hiroki SHIRATO |
| author_sort | Seishin TAKAO |
| collection | DOAJ |
| description | Precise assessment of therapeutic response in radiotherapy has been an important issue in the field of radiation oncology. This study proposed a methodology to evaluate therapeutic response based on tumor geometries. Three-dimensional (3D) tumor shapes were obtained from follow-up CT scans taken once a week throughout the treatment period. Tumor geometries were represented in two-dimensional (2D) surface geometry maps. These maps indicated the distances from the tumor center to surface at each azimuthal and horizontal angle by colors, in order to represent the characteristics of tumor morphologies. This method was applied to three clinical cases of head and neck cancer. The changes of tumor geometries could be represented visually and quantitatively using surface geometry maps. These maps provided valuable information about tumors for accurate diagnosis of tumor response to radiotherapy. |
| first_indexed | 2024-04-13T04:45:07Z |
| format | Article |
| id | doaj.art-76f1fcf41b964544b2c11e373a98af9d |
| institution | Directory Open Access Journal |
| issn | 1880-9863 |
| language | English |
| last_indexed | 2024-04-13T04:45:07Z |
| publishDate | 2009-05-01 |
| publisher | The Japan Society of Mechanical Engineers |
| record_format | Article |
| series | Journal of Biomechanical Science and Engineering |
| spelling | doaj.art-76f1fcf41b964544b2c11e373a98af9d2022-12-22T03:01:52ZengThe Japan Society of Mechanical EngineersJournal of Biomechanical Science and Engineering1880-98632009-05-014222122910.1299/jbse.4.221jbseAnalysis of Three-Dimensional Characteristics in Tumor MorphologySeishin TAKAO0Shigeru TADANO1Hiroshi TAGUCHI2Hiroki SHIRATO3Division of Human Mechanical Systems and Design, Graduate School of Engineering, Hokkaido UniversityDivision of Human Mechanical Systems and Design, Graduate School of Engineering, Hokkaido UniversityDepartment of Radiology, Hokkaido University Graduate School of MedicineDepartment of Radiology, Hokkaido University Graduate School of MedicinePrecise assessment of therapeutic response in radiotherapy has been an important issue in the field of radiation oncology. This study proposed a methodology to evaluate therapeutic response based on tumor geometries. Three-dimensional (3D) tumor shapes were obtained from follow-up CT scans taken once a week throughout the treatment period. Tumor geometries were represented in two-dimensional (2D) surface geometry maps. These maps indicated the distances from the tumor center to surface at each azimuthal and horizontal angle by colors, in order to represent the characteristics of tumor morphologies. This method was applied to three clinical cases of head and neck cancer. The changes of tumor geometries could be represented visually and quantitatively using surface geometry maps. These maps provided valuable information about tumors for accurate diagnosis of tumor response to radiotherapy.https://www.jstage.jst.go.jp/article/jbse/4/2/4_2_221/_pdf/-char/entumor geometrysurface geometry mapradiotherapytherapeutic response |
| spellingShingle | Seishin TAKAO Shigeru TADANO Hiroshi TAGUCHI Hiroki SHIRATO Analysis of Three-Dimensional Characteristics in Tumor Morphology Journal of Biomechanical Science and Engineering tumor geometry surface geometry map radiotherapy therapeutic response |
| title | Analysis of Three-Dimensional Characteristics in Tumor Morphology |
| title_full | Analysis of Three-Dimensional Characteristics in Tumor Morphology |
| title_fullStr | Analysis of Three-Dimensional Characteristics in Tumor Morphology |
| title_full_unstemmed | Analysis of Three-Dimensional Characteristics in Tumor Morphology |
| title_short | Analysis of Three-Dimensional Characteristics in Tumor Morphology |
| title_sort | analysis of three dimensional characteristics in tumor morphology |
| topic | tumor geometry surface geometry map radiotherapy therapeutic response |
| url | https://www.jstage.jst.go.jp/article/jbse/4/2/4_2_221/_pdf/-char/en |
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