Standardized Centella asiatica extract ECa 233 alleviates pain hypersensitivity by modulating P2X3 in trigeminal neuropathic pain

Standardized Centella asiatica extract ECa 233 alleviates pain hypersensitivity by modulating P2X3 in trigeminal neuropathic pain

Abstract During oral surgery and temporomandibular joint repositioning, pain hypersensitivity often occurs due to irritation or inflammation of the nerve endings in the orofacial region. Objective: This study aimed to investigate the effects of ECa 233, a Centella asiatica–standardized extract, on...

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Bibliographic Details
Main Authors: Aree Wanasuntronwong, Supassanan Kaewsrisung, Nisanat Lakkhanachatpan, Rittinarong Meepong, Tawepong Arayapisit, Mayuree Tantisira
Format: Article
Language:English
Published: University of São Paulo 2024-01-01
Series:Journal of Applied Oral Science
Subjects:
ECa 233
Infraorbital nerve chronic constriction
P2X3
NaV1
7
c-fos
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572024000100402&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572024000100402&tlng=en

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