Follow-Up of the Wheat Allergy in Children; Consequences and Outgrowing the Allergy
Allergy to wheat is a common food allergy. In spite of this fact, there is not enough literature regarding the features and outgrowing of this allergy. The objective of this study was to evaluate the manifestations of this allergy and to follow the patients to evaluate whether outgrowing allergy hap...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2012-06-01
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| Series: | Iranian Journal of Allergy, Asthma and Immunology |
| Subjects: | |
| Online Access: | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/340 |
| _version_ | 1818127287145463808 |
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| author | Mahboubeh Mansouri Zahra Pourpak Habibeh Mozafari Fatemeh Abdollah Gorji Raheleh Shokouhi Shoormasti |
| author_facet | Mahboubeh Mansouri Zahra Pourpak Habibeh Mozafari Fatemeh Abdollah Gorji Raheleh Shokouhi Shoormasti |
| author_sort | Mahboubeh Mansouri |
| collection | DOAJ |
| description | Allergy to wheat is a common food allergy. In spite of this fact, there is not enough literature regarding the features and outgrowing of this allergy. The objective of this study was to evaluate the manifestations of this allergy and to follow the patients to evaluate whether outgrowing allergy happens again and when it occurs.
Eight wheat allergic patients diagnosed between 2000 and 2001 were re-evaluated together with 13 other new cases of wheat allergy referred to the Immunology and Allergy Pediatric Department from June 2004 to March 2006. For all cases, the demographic data along with a complete history regarding allergy to wheat and other types of allergy were collected in questionnaires. The specific IgE measurements (in vivo and in vitro) and oral food challenge (in the absence of a relevant history related to allergy to wheat) were performed.
Severe anaphylaxis was seen after wheat ingestion in more than 90% of the patients. Oral tolerance to wheat developed in three patients (37.5%) out of 8 known previous cases who had been followed for eight years, the mean age of oral tolerance to wheat was 68±6.36 (range; 36 months to 108 months).
Clinical reactions in our wheat-allergic patients were more severe than those reported before. These patients were at risk for developing chronic allergic symptoms such as asthma. We also found that oral tolerance to wheat was happening in a minority of our patients. |
| first_indexed | 2024-12-11T07:14:57Z |
| format | Article |
| id | doaj.art-76f86f487fe04fa2b9148d4386edde6b |
| institution | Directory Open Access Journal |
| issn | 1735-1502 1735-5249 |
| language | English |
| last_indexed | 2024-12-11T07:14:57Z |
| publishDate | 2012-06-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Allergy, Asthma and Immunology |
| spelling | doaj.art-76f86f487fe04fa2b9148d4386edde6b2022-12-22T01:16:16ZengTehran University of Medical SciencesIranian Journal of Allergy, Asthma and Immunology1735-15021735-52492012-06-01112340Follow-Up of the Wheat Allergy in Children; Consequences and Outgrowing the AllergyMahboubeh Mansouri0Zahra Pourpak1Habibeh Mozafari2Fatemeh Abdollah Gorji3Raheleh Shokouhi Shoormasti4Department of Immunology and Allergy, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranImmunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, IranAllergy, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranAllergy, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranImmunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, IranAllergy to wheat is a common food allergy. In spite of this fact, there is not enough literature regarding the features and outgrowing of this allergy. The objective of this study was to evaluate the manifestations of this allergy and to follow the patients to evaluate whether outgrowing allergy happens again and when it occurs. Eight wheat allergic patients diagnosed between 2000 and 2001 were re-evaluated together with 13 other new cases of wheat allergy referred to the Immunology and Allergy Pediatric Department from June 2004 to March 2006. For all cases, the demographic data along with a complete history regarding allergy to wheat and other types of allergy were collected in questionnaires. The specific IgE measurements (in vivo and in vitro) and oral food challenge (in the absence of a relevant history related to allergy to wheat) were performed. Severe anaphylaxis was seen after wheat ingestion in more than 90% of the patients. Oral tolerance to wheat developed in three patients (37.5%) out of 8 known previous cases who had been followed for eight years, the mean age of oral tolerance to wheat was 68±6.36 (range; 36 months to 108 months). Clinical reactions in our wheat-allergic patients were more severe than those reported before. These patients were at risk for developing chronic allergic symptoms such as asthma. We also found that oral tolerance to wheat was happening in a minority of our patients.https://ijaai.tums.ac.ir/index.php/ijaai/article/view/340AnaphylaxisIgE mediated hypersensitivityOral toleranceWheat allergy |
| spellingShingle | Mahboubeh Mansouri Zahra Pourpak Habibeh Mozafari Fatemeh Abdollah Gorji Raheleh Shokouhi Shoormasti Follow-Up of the Wheat Allergy in Children; Consequences and Outgrowing the Allergy Iranian Journal of Allergy, Asthma and Immunology Anaphylaxis IgE mediated hypersensitivity Oral tolerance Wheat allergy |
| title | Follow-Up of the Wheat Allergy in Children; Consequences and Outgrowing the Allergy |
| title_full | Follow-Up of the Wheat Allergy in Children; Consequences and Outgrowing the Allergy |
| title_fullStr | Follow-Up of the Wheat Allergy in Children; Consequences and Outgrowing the Allergy |
| title_full_unstemmed | Follow-Up of the Wheat Allergy in Children; Consequences and Outgrowing the Allergy |
| title_short | Follow-Up of the Wheat Allergy in Children; Consequences and Outgrowing the Allergy |
| title_sort | follow up of the wheat allergy in children consequences and outgrowing the allergy |
| topic | Anaphylaxis IgE mediated hypersensitivity Oral tolerance Wheat allergy |
| url | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/340 |
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