Impact of the addition of dexmedetomidine to patient-controlled intravenous analgesia on postoperative pain-sleep interaction cycle and delirium: A systematic review and meta-analysis of randomized controlled trials

Impact of the addition of dexmedetomidine to patient-controlled intravenous analgesia on postoperative pain-sleep interaction cycle and delirium: A systematic review and meta-analysis of randomized controlled trials

Background: The reciprocal nexus between sleep and pain is well-documented, with the deleterious impact of operative trauma potentially playing a pivotal role in the dysregulation of this interplay, which could significantly contribute to the manifestation of postoperative delirium (POD). Studies ha...

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Bibliographic Details
Main Authors: Wenjie Xu, Yuxiang Zheng, Qing Wang, Zizheng Suo, Lingling Fang, Jing Yang, Shuai Li, Peng Li, Xixi Jia, Xiaoyan Liu, Hui Zheng, Cheng Ni
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Dexmedetomidine
Patient-controlled intravenous analgesia
Sleep disturbance
Pain-sleep interaction cycle
Postoperative delirium
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024036545

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