Oleocanthal Inhibits Catabolic and Inflammatory Mediators in LPS-Activated Human Primary Osteoarthritis (OA) Chondrocytes Through MAPKs/NF-κB Pathways

Oleocanthal Inhibits Catabolic and Inflammatory Mediators in LPS-Activated Human Primary Osteoarthritis (OA) Chondrocytes Through MAPKs/NF-κB Pathways

Background/Aims: Oleocanthal (OC), a phenolic compound present in extra virgin olive oil (EVOO), has attracted attention since its discovery for its relevant pharmacological properties in different pathogenic processes, including inflammation. Here, we investigated the involvement of OC in LPS-activ...

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Bibliographic Details
Main Authors: Morena Scotece, Javier Conde, Vanessa Abella, Veronica López, Vera Francisco, Clara Ruiz, Victor Campos, Francisca Lago, Rodolfo Gomez, Jesús Pino, Oreste Gualillo
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Oleocanthal
Chondrocytes
Phenolic component
Inflammation
Osteoarthritis
Online Access:https://www.karger.com/Article/FullText/493840

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