The U2AF65/circNCAPG/RREB1 feedback loop promotes malignant phenotypes of glioma stem cells through activating the TGF-β pathway

The U2AF65/circNCAPG/RREB1 feedback loop promotes malignant phenotypes of glioma stem cells through activating the TGF-β pathway

Abstract Glioma is the most aggressive and common malignant neoplasms in human brain tumors. Numerous studies have showed that glioma stem cells (GSCs)drive the malignant progression of gliomas. Recent studies have revealed that circRNAs can maintain stemness and promote malignant progression of gli...

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Bibliographic Details
Main Authors: Hao Li, Yang Jiang, Jinpeng Hu, Jinkun Xu, Lian Chen, Guoqing Zhang, Junshuang Zhao, Shengliang Zong, Zhengting Guo, Xinqiao Li, Xiang Zhao, Zhitao Jing
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05556-y

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