Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients

Background: Asthma is an allergic hypersensitivity disease in which many mediators play a role in its pathogenecity. One of these etiological agents is the mediators such as Interleukin-5 (IL-5). The  aim of this study to demonstrate the association between IL-5 and obesity in asthma development....

Full description

Bibliographic Details
Main Authors: Yacoob Y. Al-Rubayei, Batool A. Al-Haidary, Wala'a E. Jasim
Format: Article
Language:English
Published: College of Medicine University of Baghdad 2007-04-01
Series:مجلة كلية الطب
Subjects:
Online Access:http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1430
Description
Summary:Background: Asthma is an allergic hypersensitivity disease in which many mediators play a role in its pathogenecity. One of these etiological agents is the mediators such as Interleukin-5 (IL-5). The  aim of this study to demonstrate the association between IL-5 and obesity in asthma development.  Materials & Methods: One hundred and four sera samples for asthma cases have been studied in comparison with 41 non-asthmatic bronchitis as a patient controls beside 30 apparently healthy controls. Cytokine has been estimated using ELISA method in correlation with Body Mass Index (BMI). Results: This study revealed a significant correlation between IL-5 concentration and BMI (P<0.05), particularly among females. Conclusion: There is certain correlation between obesity and asthma accompanied by IL-5.
ISSN:0041-9419
2410-8057