Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients

Background: Asthma is an allergic hypersensitivity disease in which many mediators play a role in its pathogenecity. One of these etiological agents is the mediators such as Interleukin-5 (IL-5). The  aim of this study to demonstrate the association between IL-5 and obesity in asthma development....

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Main Authors: Yacoob Y. Al-Rubayei, Batool A. Al-Haidary, Wala'a E. Jasim
Format: Article
Language:English
Published: College of Medicine University of Baghdad 2007-04-01
Series:مجلة كلية الطب
Subjects:
Online Access:http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1430
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author Yacoob Y. Al-Rubayei
Batool A. Al-Haidary
Wala'a E. Jasim
author_facet Yacoob Y. Al-Rubayei
Batool A. Al-Haidary
Wala'a E. Jasim
author_sort Yacoob Y. Al-Rubayei
collection DOAJ
description Background: Asthma is an allergic hypersensitivity disease in which many mediators play a role in its pathogenecity. One of these etiological agents is the mediators such as Interleukin-5 (IL-5). The  aim of this study to demonstrate the association between IL-5 and obesity in asthma development.  Materials & Methods: One hundred and four sera samples for asthma cases have been studied in comparison with 41 non-asthmatic bronchitis as a patient controls beside 30 apparently healthy controls. Cytokine has been estimated using ELISA method in correlation with Body Mass Index (BMI). Results: This study revealed a significant correlation between IL-5 concentration and BMI (P<0.05), particularly among females. Conclusion: There is certain correlation between obesity and asthma accompanied by IL-5.
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spelling doaj.art-770a94db75c64a36b65878bbd26ca90b2024-02-02T20:54:21ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572007-04-01491Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic PatientsYacoob Y. Al-Rubayei0Batool A. Al-Haidary1Wala'a E. Jasim2Medical Laboratory Science Technology / College of Medical & Health Technology.Clinical Immunology / Assist. Prof. / College of Medical & Health Technology.Biochemistry / Assist. Prof./ College of Medical & Health Technology.Background: Asthma is an allergic hypersensitivity disease in which many mediators play a role in its pathogenecity. One of these etiological agents is the mediators such as Interleukin-5 (IL-5). The  aim of this study to demonstrate the association between IL-5 and obesity in asthma development.  Materials & Methods: One hundred and four sera samples for asthma cases have been studied in comparison with 41 non-asthmatic bronchitis as a patient controls beside 30 apparently healthy controls. Cytokine has been estimated using ELISA method in correlation with Body Mass Index (BMI). Results: This study revealed a significant correlation between IL-5 concentration and BMI (P<0.05), particularly among females. Conclusion: There is certain correlation between obesity and asthma accompanied by IL-5.http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1430Asthma, IL-5, ELISA, BMI.
spellingShingle Yacoob Y. Al-Rubayei
Batool A. Al-Haidary
Wala'a E. Jasim
Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients
مجلة كلية الطب
Asthma, IL-5, ELISA, BMI.
title Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients
title_full Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients
title_fullStr Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients
title_full_unstemmed Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients
title_short Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients
title_sort association between interleukin 5 body mass index among iraqi asthmatic patients
topic Asthma, IL-5, ELISA, BMI.
url http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1430
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