Saving lives: Long-term morbidity and mortality trials with selective angiotensin receptor blocker therapy
Summary Prospective randomised trials have demonstrated convincingly the benefits of drug treatment of hypertension. Treatment with conventional antihypertensive agents reduces the incidence of cardiovascular events by about that which would be expected from epidemiological data for the achieved dif...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publications
2000-06-01
|
| Series: | Journal of the Renin-Angiotensin-Aldosterone System |
| Online Access: | https://doi.org/10.3317/JRAAS.2000.048 |
| _version_ | 1797283603389874176 |
|---|---|
| author | Gordon T McInnes |
| author_facet | Gordon T McInnes |
| author_sort | Gordon T McInnes |
| collection | DOAJ |
| description | Summary Prospective randomised trials have demonstrated convincingly the benefits of drug treatment of hypertension. Treatment with conventional antihypertensive agents reduces the incidence of cardiovascular events by about that which would be expected from epidemiological data for the achieved difference in blood pressure. Newer agents, such as angiotensin II receptor blockers, have potential for benefits beyond blood pressure reduction. This rationale is under evaluation in a number of long-term morbidity and mortality trials which will report over the next few years, with the largest, VALUE, due to provide results in 2004. The findings from these trials will be decisive in determining the future role of this important new class of drugs. |
| first_indexed | 2024-03-07T17:33:06Z |
| format | Article |
| id | doaj.art-770b0d7b3b1d4871942c339378847cb1 |
| institution | Directory Open Access Journal |
| issn | 1470-3203 1752-8976 |
| language | English |
| last_indexed | 2024-03-07T17:33:06Z |
| publishDate | 2000-06-01 |
| publisher | SAGE Publications |
| record_format | Article |
| series | Journal of the Renin-Angiotensin-Aldosterone System |
| spelling | doaj.art-770b0d7b3b1d4871942c339378847cb12024-03-02T17:25:29ZengSAGE PublicationsJournal of the Renin-Angiotensin-Aldosterone System1470-32031752-89762000-06-01110.3317/JRAAS.2000.04810.3317_JRAAS.2000.048Saving lives: Long-term morbidity and mortality trials with selective angiotensin receptor blocker therapyGordon T McInnes0University of Glasgow, Department of Medicine and Therapeutics, Western Infirmary, Glasgow, G11 6NT, UKSummary Prospective randomised trials have demonstrated convincingly the benefits of drug treatment of hypertension. Treatment with conventional antihypertensive agents reduces the incidence of cardiovascular events by about that which would be expected from epidemiological data for the achieved difference in blood pressure. Newer agents, such as angiotensin II receptor blockers, have potential for benefits beyond blood pressure reduction. This rationale is under evaluation in a number of long-term morbidity and mortality trials which will report over the next few years, with the largest, VALUE, due to provide results in 2004. The findings from these trials will be decisive in determining the future role of this important new class of drugs.https://doi.org/10.3317/JRAAS.2000.048 |
| spellingShingle | Gordon T McInnes Saving lives: Long-term morbidity and mortality trials with selective angiotensin receptor blocker therapy Journal of the Renin-Angiotensin-Aldosterone System |
| title | Saving lives: Long-term morbidity and mortality trials with selective angiotensin receptor blocker therapy |
| title_full | Saving lives: Long-term morbidity and mortality trials with selective angiotensin receptor blocker therapy |
| title_fullStr | Saving lives: Long-term morbidity and mortality trials with selective angiotensin receptor blocker therapy |
| title_full_unstemmed | Saving lives: Long-term morbidity and mortality trials with selective angiotensin receptor blocker therapy |
| title_short | Saving lives: Long-term morbidity and mortality trials with selective angiotensin receptor blocker therapy |
| title_sort | saving lives long term morbidity and mortality trials with selective angiotensin receptor blocker therapy |
| url | https://doi.org/10.3317/JRAAS.2000.048 |
| work_keys_str_mv | AT gordontmcinnes savingliveslongtermmorbidityandmortalitytrialswithselectiveangiotensinreceptorblockertherapy |