IgG4-related inflammatory pseudotumour of the gallbladder in acute cholecystitis
Immunoglobulin G4 related pseudotumour (IgG4-PT) of the gallbladder is a very rare condition formed by the infiltration of IgG4-positive lymphocytes and plasma cells, resulting in a mass effect that can mimic malignancy. We present a case of a patient who underwent an unremarkable laparoscopic chole...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-09-01
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| Series: | Human Pathology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772736X23000221 |
| _version_ | 1797690865708171264 |
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| author | Walter Santucci Philip Lee Rosanne Devadas Henry To |
| author_facet | Walter Santucci Philip Lee Rosanne Devadas Henry To |
| author_sort | Walter Santucci |
| collection | DOAJ |
| description | Immunoglobulin G4 related pseudotumour (IgG4-PT) of the gallbladder is a very rare condition formed by the infiltration of IgG4-positive lymphocytes and plasma cells, resulting in a mass effect that can mimic malignancy. We present a case of a patient who underwent an unremarkable laparoscopic cholecystectomy for symptoms of early cholecystitis that was incidentally found to have an inflammatory tumour adjacent to the cystic duct. Identification remains difficult and histopathology remains a cornerstone in correct diagnosis. Histopathological confirmation is based on meeting two of three histological criteria in the correct clinical context. IgG4-PT is a rare cause of cholecystitis and requires ongoing surveillance for IgG4 cholangiopathy. |
| first_indexed | 2024-03-12T02:05:15Z |
| format | Article |
| id | doaj.art-770caa958d974faaa4fc2862f27ff109 |
| institution | Directory Open Access Journal |
| issn | 2772-736X |
| language | English |
| last_indexed | 2024-03-12T02:05:15Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Human Pathology Reports |
| spelling | doaj.art-770caa958d974faaa4fc2862f27ff1092023-09-07T04:45:13ZengElsevierHuman Pathology Reports2772-736X2023-09-0133300712IgG4-related inflammatory pseudotumour of the gallbladder in acute cholecystitisWalter Santucci0Philip Lee1Rosanne Devadas2Henry To3Department of Surgery, Werribee Mercy Hospital, Werribee, VIC, Australia; Corresponding author at: Department of Surgery, Level 2 Werribee Mercy Hospital, 300-310 Princes Highway, Werribee, VIC 3030, Australia.Melbourne Clinical School, School of Medicine, The University of Notre Dame Australia, Werribee, VIC, AustraliaDorevitch Pathology, Heidelberg, VIC, AustraliaDepartment of Surgery, Werribee Mercy Hospital, Werribee, VIC, AustraliaImmunoglobulin G4 related pseudotumour (IgG4-PT) of the gallbladder is a very rare condition formed by the infiltration of IgG4-positive lymphocytes and plasma cells, resulting in a mass effect that can mimic malignancy. We present a case of a patient who underwent an unremarkable laparoscopic cholecystectomy for symptoms of early cholecystitis that was incidentally found to have an inflammatory tumour adjacent to the cystic duct. Identification remains difficult and histopathology remains a cornerstone in correct diagnosis. Histopathological confirmation is based on meeting two of three histological criteria in the correct clinical context. IgG4-PT is a rare cause of cholecystitis and requires ongoing surveillance for IgG4 cholangiopathy.http://www.sciencedirect.com/science/article/pii/S2772736X23000221IgG4 pseudotumourIgG4 cholecystitisCystic duct tumoursGallbladder tumours |
| spellingShingle | Walter Santucci Philip Lee Rosanne Devadas Henry To IgG4-related inflammatory pseudotumour of the gallbladder in acute cholecystitis Human Pathology Reports IgG4 pseudotumour IgG4 cholecystitis Cystic duct tumours Gallbladder tumours |
| title | IgG4-related inflammatory pseudotumour of the gallbladder in acute cholecystitis |
| title_full | IgG4-related inflammatory pseudotumour of the gallbladder in acute cholecystitis |
| title_fullStr | IgG4-related inflammatory pseudotumour of the gallbladder in acute cholecystitis |
| title_full_unstemmed | IgG4-related inflammatory pseudotumour of the gallbladder in acute cholecystitis |
| title_short | IgG4-related inflammatory pseudotumour of the gallbladder in acute cholecystitis |
| title_sort | igg4 related inflammatory pseudotumour of the gallbladder in acute cholecystitis |
| topic | IgG4 pseudotumour IgG4 cholecystitis Cystic duct tumours Gallbladder tumours |
| url | http://www.sciencedirect.com/science/article/pii/S2772736X23000221 |
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