Monitoring mandibular movements to detect Cheyne-Stokes Breathing
Abstract Background The patterns of mandibular movements (MM) during sleep can be used to identify increased respiratory effort periodic large-amplitude MM (LPM), and cortical arousals associated with “sharp” large-amplitude MM (SPM). We hypothesized that Cheyne Stokes breathing (CSB) may be identif...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2017-04-01
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| Series: | Respiratory Research |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12931-017-0551-8 |
| _version_ | 1818260698737672192 |
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| author | Jean-Benoît Martinot Jean-Christian Borel Nhat-Nam Le-Dong Hervé Jean-Pierre Guénard Valerie Cuthbert Philip E. Silkoff David Gozal Jean-Louis Pepin |
| author_facet | Jean-Benoît Martinot Jean-Christian Borel Nhat-Nam Le-Dong Hervé Jean-Pierre Guénard Valerie Cuthbert Philip E. Silkoff David Gozal Jean-Louis Pepin |
| author_sort | Jean-Benoît Martinot |
| collection | DOAJ |
| description | Abstract Background The patterns of mandibular movements (MM) during sleep can be used to identify increased respiratory effort periodic large-amplitude MM (LPM), and cortical arousals associated with “sharp” large-amplitude MM (SPM). We hypothesized that Cheyne Stokes breathing (CSB) may be identified by periodic abnormal MM patterns. The present study aims to evaluate prospectively the concordance between CSB detected by periodic MM and polysomnography (PSG) as gold-standard. The present study aims to evaluate prospectively the concordance between CSB detected by periodic MM and polysomnography (PSG) as gold-standard. Methods In 573 consecutive patients attending an in-laboratory PSG for suspected sleep disordered breathing (SDB), MM signals were acquired using magnetometry and scored manually while blinded from the PSG signal. Data analysis aimed to verify the concordance between the CSB identified by PSG and the presence of LPM or SPM. The data were randomly divided into training and validation sets (985 5-min segments/set) and concordance was evaluated using 2 classification models. Results In PSG, 22 patients (mean age ± SD: 65.9 ± 15.0 with a sex ratio M/F of 17/5) had CSB (mean central apnea hourly indice ± SD: 17.5 ± 6.2) from a total of 573 patients with suspected SDB. When tested on independent subset, the classification of CSB based on LPM and SPM is highly accurate (Balanced-accuracy = 0.922, sensitivity = 0.922, specificity = 0.921 and error-rate = 0.078). Logistic models based odds-ratios for CSB in presence of SPM or LPM were 172.43 (95% CI: 88.23–365.04; p < 0.001) and 186.79 (95% CI: 100.48–379.93; p < 0.001), respectively. Conclusion CSB in patients with sleep disordered breathing could be accurately identified by a simple magnetometer device recording mandibular movements. |
| first_indexed | 2024-12-12T18:35:28Z |
| format | Article |
| id | doaj.art-770ed6687a224b92bbb5b72cdf3d6a65 |
| institution | Directory Open Access Journal |
| issn | 1465-993X |
| language | English |
| last_indexed | 2024-12-12T18:35:28Z |
| publishDate | 2017-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Respiratory Research |
| spelling | doaj.art-770ed6687a224b92bbb5b72cdf3d6a652022-12-22T00:15:48ZengBMCRespiratory Research1465-993X2017-04-011811910.1186/s12931-017-0551-8Monitoring mandibular movements to detect Cheyne-Stokes BreathingJean-Benoît Martinot0Jean-Christian Borel1Nhat-Nam Le-Dong2Hervé Jean-Pierre Guénard3Valerie Cuthbert4Philip E. Silkoff5David Gozal6Jean-Louis Pepin7Centre du Sommeil et de la Vigilance, CHU UCL Namur Site Ste ElisabethAGIR à dom. AssociationRespiSomLaboratory of Physiology, Bordeaux UniversityCentre du Sommeil et de la Vigilance, CHU UCL Namur Site Ste ElisabethTemple UniversityUniversity of ChicagoUniversity Grenoble AlpesAbstract Background The patterns of mandibular movements (MM) during sleep can be used to identify increased respiratory effort periodic large-amplitude MM (LPM), and cortical arousals associated with “sharp” large-amplitude MM (SPM). We hypothesized that Cheyne Stokes breathing (CSB) may be identified by periodic abnormal MM patterns. The present study aims to evaluate prospectively the concordance between CSB detected by periodic MM and polysomnography (PSG) as gold-standard. The present study aims to evaluate prospectively the concordance between CSB detected by periodic MM and polysomnography (PSG) as gold-standard. Methods In 573 consecutive patients attending an in-laboratory PSG for suspected sleep disordered breathing (SDB), MM signals were acquired using magnetometry and scored manually while blinded from the PSG signal. Data analysis aimed to verify the concordance between the CSB identified by PSG and the presence of LPM or SPM. The data were randomly divided into training and validation sets (985 5-min segments/set) and concordance was evaluated using 2 classification models. Results In PSG, 22 patients (mean age ± SD: 65.9 ± 15.0 with a sex ratio M/F of 17/5) had CSB (mean central apnea hourly indice ± SD: 17.5 ± 6.2) from a total of 573 patients with suspected SDB. When tested on independent subset, the classification of CSB based on LPM and SPM is highly accurate (Balanced-accuracy = 0.922, sensitivity = 0.922, specificity = 0.921 and error-rate = 0.078). Logistic models based odds-ratios for CSB in presence of SPM or LPM were 172.43 (95% CI: 88.23–365.04; p < 0.001) and 186.79 (95% CI: 100.48–379.93; p < 0.001), respectively. Conclusion CSB in patients with sleep disordered breathing could be accurately identified by a simple magnetometer device recording mandibular movements.http://link.springer.com/article/10.1186/s12931-017-0551-8Central sleep apnea syndromeCheyne Stokes breathingSleep mandibular movementsPolysomnography |
| spellingShingle | Jean-Benoît Martinot Jean-Christian Borel Nhat-Nam Le-Dong Hervé Jean-Pierre Guénard Valerie Cuthbert Philip E. Silkoff David Gozal Jean-Louis Pepin Monitoring mandibular movements to detect Cheyne-Stokes Breathing Respiratory Research Central sleep apnea syndrome Cheyne Stokes breathing Sleep mandibular movements Polysomnography |
| title | Monitoring mandibular movements to detect Cheyne-Stokes Breathing |
| title_full | Monitoring mandibular movements to detect Cheyne-Stokes Breathing |
| title_fullStr | Monitoring mandibular movements to detect Cheyne-Stokes Breathing |
| title_full_unstemmed | Monitoring mandibular movements to detect Cheyne-Stokes Breathing |
| title_short | Monitoring mandibular movements to detect Cheyne-Stokes Breathing |
| title_sort | monitoring mandibular movements to detect cheyne stokes breathing |
| topic | Central sleep apnea syndrome Cheyne Stokes breathing Sleep mandibular movements Polysomnography |
| url | http://link.springer.com/article/10.1186/s12931-017-0551-8 |
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