Estimating Transition Probabilities Across the Alzheimer’s Disease Continuum Using a Nationally Representative Real-World Database in the United States

Estimating Transition Probabilities Across the Alzheimer’s Disease Continuum Using a Nationally Representative Real-World Database in the United States

Abstract Introduction Clinical Alzheimer’s disease (AD) begins with mild cognitive impairment (MCI) and progresses to mild, moderate, or severe dementia, constituting a disease continuum that eventually leads to death. This study aimed to estimate the probabilities of transitions across those diseas...

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Bibliographic Details
Main Authors: Amir Abbas Tahami Monfared, Shuai Fu, Noemi Hummel, Luyuan Qi, Aastha Chandak, Raymond Zhang, Quanwu Zhang
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-05-01
Series:Neurology and Therapy
Subjects:
Alzheimer’s disease
Disease progression
Mixed-effects model
Multi-state Markov model
TICS-m
Transition probability
Online Access:https://doi.org/10.1007/s40120-023-00498-1

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