Azilsartan Improves Salt Sensitivity by Modulating the Proximal Tubular Na+-H+ Exchanger-3 in Mice.

Azilsartan Improves Salt Sensitivity by Modulating the Proximal Tubular Na+-H+ Exchanger-3 in Mice.

A potent angiotensin II type-1 receptor blocker, azilsartan, has been reported to reduce blood pressure more effectively than candesartan. Interestingly, azilsartan can also restore the circadian rhythm of blood pressure. We hypothesized that azilsartan could also improve salt sensitivity; thus, we...

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Bibliographic Details
Main Authors: Masaki Hatanaka, Jun-Ya Kaimori, Satoko Yamamoto, Isao Matsui, Takayuki Hamano, Yoshitsugu Takabatake, Carolyn M Ecelbarger, Shiro Takahara, Yoshitaka Isaka, Hiromi Rakugi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4725961?pdf=render

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